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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF4E3 All Species: 0
Human Site: S103 Identified Species: 0
UniProt: Q8N5X7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5X7 NP_001128121.1 224 24441 S103 T S L P L R C S Y H L M R G E
Chimpanzee Pan troglodytes XP_526229 376 41048
Rhesus Macaque Macaca mulatta XP_001084944 264 28611
Dog Lupus familis XP_541806 183 20579
Cat Felis silvestris
Mouse Mus musculus Q9DBB5 207 22818
Rat Rattus norvegicus P63074 217 25035
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509774 252 27662
Chicken Gallus gallus
Frog Xenopus laevis Q6GR08 218 24796
Zebra Danio Brachydanio rerio Q66HY7 224 25384
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48598 259 29205
Honey Bee Apis mellifera XP_392604 210 24074
Nematode Worm Caenorhab. elegans O61955 248 27791
Sea Urchin Strong. purpuratus NP_001091926 211 24181
Poplar Tree Populus trichocarpa
Maize Zea mays O81481 218 24452
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FK59 221 25726
Baker's Yeast Sacchar. cerevisiae P07260 213 24236
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.1 69.6 75.4 N.A. 87.9 28.1 N.A. 63 N.A. 73.2 70 N.A. 24.7 47.3 28.2 49.5
Protein Similarity: 100 54.5 72.3 78.5 N.A. 90.1 43.7 N.A. 72.2 N.A. 80.8 78.1 N.A. 44.4 64.7 42.7 66.5
P-Site Identity: 100 0 0 0 N.A. 0 0 N.A. 0 N.A. 0 0 N.A. 0 0 0 0
P-Site Similarity: 100 0 0 0 N.A. 0 0 N.A. 0 N.A. 0 0 N.A. 0 0 0 0
Percent
Protein Identity: N.A. 29.4 N.A. 28.1 26.3 N.A.
Protein Similarity: N.A. 46.8 N.A. 48.2 43.3 N.A.
P-Site Identity: N.A. 0 N.A. 0 0 N.A.
P-Site Similarity: N.A. 0 N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 100 0 100 0 0 0 0 0 100 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 100 0 0 0 0 0 0 100 0 0 % R
% Ser: 0 100 0 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _