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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E3
All Species:
6.06
Human Site:
S19
Identified Species:
8.89
UniProt:
Q8N5X7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5X7
NP_001128121.1
224
24441
S19
G
A
R
E
P
P
G
S
R
A
A
A
A
A
A
Chimpanzee
Pan troglodytes
XP_526229
376
41048
A121
G
A
P
T
P
C
P
A
A
G
A
V
D
S
S
Rhesus Macaque
Macaca mulatta
XP_001084944
264
28611
A60
G
A
P
T
P
C
P
A
A
A
A
V
D
S
S
Dog
Lupus familis
XP_541806
183
20579
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBB5
207
22818
Rat
Rattus norvegicus
P63074
217
25035
T9
A
T
V
E
P
E
T
T
P
T
T
N
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509774
252
27662
C42
T
S
R
P
W
Q
G
C
P
S
S
S
S
V
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR08
218
24796
P16
D
R
R
L
Q
P
E
P
D
E
Q
L
H
L
N
Zebra Danio
Brachydanio rerio
Q66HY7
224
25384
R15
N
L
Q
L
N
T
A
R
Q
S
S
P
V
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
S35
G
R
P
E
P
P
T
S
A
A
A
P
A
E
A
Honey Bee
Apis mellifera
XP_392604
210
24074
T14
E
S
K
D
D
N
A
T
N
L
S
E
T
L
V
Nematode Worm
Caenorhab. elegans
O61955
248
27791
N8
M
S
T
S
V
A
E
N
K
A
L
S
A
S
G
Sea Urchin
Strong. purpuratus
NP_001091926
211
24181
S8
M
A
T
S
E
F
V
S
S
A
I
Q
R
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FK59
221
25726
M17
E
I
R
D
S
G
N
M
D
S
I
K
S
H
Y
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
K8
M
S
V
E
E
V
S
K
K
F
E
E
N
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.1
69.6
75.4
N.A.
87.9
28.1
N.A.
63
N.A.
73.2
70
N.A.
24.7
47.3
28.2
49.5
Protein Similarity:
100
54.5
72.3
78.5
N.A.
90.1
43.7
N.A.
72.2
N.A.
80.8
78.1
N.A.
44.4
64.7
42.7
66.5
P-Site Identity:
100
26.6
33.3
0
N.A.
0
13.3
N.A.
20
N.A.
13.3
0
N.A.
60
0
13.3
20
P-Site Similarity:
100
46.6
53.3
0
N.A.
0
20
N.A.
53.3
N.A.
13.3
33.3
N.A.
60
33.3
46.6
20
Percent
Protein Identity:
N.A.
29.4
N.A.
28.1
26.3
N.A.
Protein Similarity:
N.A.
46.8
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
25
0
0
0
7
13
13
19
32
25
7
19
7
19
% A
% Cys:
0
0
0
0
0
13
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
13
7
0
0
0
13
0
0
0
13
0
0
% D
% Glu:
13
0
0
25
13
7
13
0
0
7
7
13
0
7
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% F
% Gly:
25
0
0
0
0
7
13
0
0
7
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
13
0
0
0
0
% I
% Lys:
0
0
7
0
0
0
0
7
13
0
0
7
0
0
0
% K
% Leu:
0
7
0
13
0
0
0
0
0
7
7
7
0
13
0
% L
% Met:
19
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
7
7
7
7
0
0
7
7
7
7
% N
% Pro:
0
0
19
7
32
19
13
7
13
0
0
13
7
7
7
% P
% Gln:
0
0
7
0
7
7
0
0
7
0
7
7
0
7
7
% Q
% Arg:
0
13
25
0
0
0
0
7
7
0
0
0
7
0
0
% R
% Ser:
0
25
0
13
7
0
7
19
7
19
19
13
13
19
25
% S
% Thr:
7
7
13
13
0
7
13
13
0
7
7
0
7
0
0
% T
% Val:
0
0
13
0
7
7
7
0
0
0
0
13
7
13
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _