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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E3
All Species:
3.94
Human Site:
S38
Identified Species:
5.78
UniProt:
Q8N5X7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5X7
NP_001128121.1
224
24441
S38
P
L
G
L
Q
Q
L
S
A
L
Q
P
E
P
G
Chimpanzee
Pan troglodytes
XP_526229
376
41048
V190
Q
V
T
G
K
R
G
V
A
A
G
C
P
G
F
Rhesus Macaque
Macaca mulatta
XP_001084944
264
28611
E78
S
S
S
T
G
Q
P
E
L
L
I
Q
C
R
E
Dog
Lupus familis
XP_541806
183
20579
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBB5
207
22818
A22
P
L
D
K
A
L
S
A
L
P
P
E
P
G
G
Rat
Rattus norvegicus
P63074
217
25035
N25
E
E
E
K
T
E
S
N
Q
E
V
A
N
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509774
252
27662
T66
W
G
P
L
P
L
P
T
N
G
K
T
Y
S
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR08
218
24796
L32
Q
D
I
G
E
L
G
L
P
Q
E
P
D
T
E
Zebra Danio
Brachydanio rerio
Q66HY7
224
25384
T38
E
R
E
L
E
N
I
T
N
H
V
E
D
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
G69
A
T
T
T
A
P
A
G
D
D
A
V
R
T
E
Honey Bee
Apis mellifera
XP_392604
210
24074
T29
F
S
N
E
T
V
K
T
I
E
E
H
E
T
S
Nematode Worm
Caenorhab. elegans
O61955
248
27791
S23
D
V
N
A
S
D
A
S
V
P
P
E
L
L
T
Sea Urchin
Strong. purpuratus
NP_001091926
211
24181
D27
I
S
F
E
G
L
A
D
R
V
V
A
Q
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
A34
E
G
E
I
T
D
L
A
C
A
P
S
P
P
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FK59
221
25726
R34
D
S
V
S
E
E
R
R
S
R
E
L
K
D
G
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
L27
T
A
T
P
K
T
V
L
S
D
S
A
H
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.1
69.6
75.4
N.A.
87.9
28.1
N.A.
63
N.A.
73.2
70
N.A.
24.7
47.3
28.2
49.5
Protein Similarity:
100
54.5
72.3
78.5
N.A.
90.1
43.7
N.A.
72.2
N.A.
80.8
78.1
N.A.
44.4
64.7
42.7
66.5
P-Site Identity:
100
6.6
13.3
0
N.A.
20
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
26.6
13.3
0
N.A.
26.6
20
N.A.
20
N.A.
26.6
33.3
N.A.
0
20
13.3
13.3
Percent
Protein Identity:
N.A.
29.4
N.A.
28.1
26.3
N.A.
Protein Similarity:
N.A.
46.8
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
13
0
19
13
13
13
7
19
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% C
% Asp:
13
7
7
0
0
13
0
7
7
13
0
0
13
7
7
% D
% Glu:
19
7
19
13
19
13
0
7
0
13
19
19
13
7
32
% E
% Phe:
7
0
7
0
0
0
0
0
0
0
0
0
0
7
7
% F
% Gly:
0
13
7
13
13
0
13
7
0
7
7
0
0
19
19
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
7
7
0
0
% H
% Ile:
7
0
7
7
0
0
7
0
7
0
7
0
0
0
0
% I
% Lys:
0
0
0
13
13
0
7
0
0
0
7
0
7
0
0
% K
% Leu:
0
13
0
19
0
25
13
13
13
13
0
7
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
7
0
7
13
0
0
0
7
0
0
% N
% Pro:
13
0
7
7
7
7
13
0
7
13
19
13
19
19
7
% P
% Gln:
13
0
0
0
7
13
0
0
7
7
7
7
7
0
0
% Q
% Arg:
0
7
0
0
0
7
7
7
7
7
0
0
7
7
0
% R
% Ser:
7
25
7
7
7
0
13
13
13
0
7
7
0
7
7
% S
% Thr:
7
7
19
13
19
7
0
19
0
0
0
7
0
19
13
% T
% Val:
0
13
7
0
0
7
7
7
7
7
19
7
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _