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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E3
All Species:
9.09
Human Site:
S97
Identified Species:
13.33
UniProt:
Q8N5X7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5X7
NP_001128121.1
224
24441
S97
N
N
I
P
P
V
T
S
L
P
L
R
C
S
Y
Chimpanzee
Pan troglodytes
XP_526229
376
41048
S249
N
N
I
P
P
V
T
S
L
P
L
R
C
S
Y
Rhesus Macaque
Macaca mulatta
XP_001084944
264
28611
S137
N
N
I
P
P
V
T
S
L
P
L
R
C
S
Y
Dog
Lupus familis
XP_541806
183
20579
M66
L
R
C
S
Y
H
L
M
R
G
E
R
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBB5
207
22818
L81
N
I
P
P
V
T
S
L
P
L
R
C
S
Y
H
Rat
Rattus norvegicus
P63074
217
25035
N84
N
H
I
Q
L
S
S
N
L
M
P
G
C
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509774
252
27662
N125
N
N
I
P
P
V
P
N
L
P
L
R
C
S
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR08
218
24796
N91
N
N
I
P
L
V
T
N
L
P
V
R
W
S
Y
Zebra Danio
Brachydanio rerio
Q66HY7
224
25384
C97
N
N
I
P
P
V
S
C
L
P
L
R
C
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
E128
N
H
I
K
P
P
S
E
I
K
L
G
S
D
Y
Honey Bee
Apis mellifera
XP_392604
210
24074
A88
N
N
I
P
S
V
S
A
V
Q
V
R
Y
S
Y
Nematode Worm
Caenorhab. elegans
O61955
248
27791
W82
Q
S
A
G
G
L
N
W
G
S
D
Y
Y
L
F
Sea Urchin
Strong. purpuratus
NP_001091926
211
24181
D86
N
N
I
P
D
A
S
D
L
P
L
R
F
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
K93
N
N
I
N
H
P
S
K
L
I
V
G
A
D
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FK59
221
25726
L93
C
H
L
A
R
S
S
L
L
P
S
P
T
D
L
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
E86
Q
N
I
P
E
P
H
E
L
P
L
K
S
D
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.1
69.6
75.4
N.A.
87.9
28.1
N.A.
63
N.A.
73.2
70
N.A.
24.7
47.3
28.2
49.5
Protein Similarity:
100
54.5
72.3
78.5
N.A.
90.1
43.7
N.A.
72.2
N.A.
80.8
78.1
N.A.
44.4
64.7
42.7
66.5
P-Site Identity:
100
100
100
6.6
N.A.
13.3
33.3
N.A.
86.6
N.A.
73.3
86.6
N.A.
33.3
53.3
0
66.6
P-Site Similarity:
100
100
100
6.6
N.A.
26.6
53.3
N.A.
93.3
N.A.
86.6
93.3
N.A.
53.3
80
20
73.3
Percent
Protein Identity:
N.A.
29.4
N.A.
28.1
26.3
N.A.
Protein Similarity:
N.A.
46.8
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
26.6
N.A.
13.3
46.6
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
7
0
7
0
0
0
0
7
0
0
% A
% Cys:
7
0
7
0
0
0
0
7
0
0
0
7
38
0
0
% C
% Asp:
0
0
0
0
7
0
0
7
0
0
7
0
0
32
0
% D
% Glu:
0
0
0
0
7
0
0
13
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
13
% F
% Gly:
0
0
0
7
7
0
0
0
7
7
0
19
0
0
0
% G
% His:
0
19
0
0
7
7
7
0
0
0
0
0
0
0
7
% H
% Ile:
0
7
75
0
0
0
0
0
7
7
0
0
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
7
0
7
0
7
0
0
0
% K
% Leu:
7
0
7
0
13
7
7
13
69
7
50
0
0
7
13
% L
% Met:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% M
% Asn:
75
63
0
7
0
0
7
19
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
63
38
19
7
0
7
57
7
7
0
7
0
% P
% Gln:
13
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
7
0
0
7
0
0
0
7
0
7
57
7
0
0
% R
% Ser:
0
7
0
7
7
13
50
19
0
7
7
0
19
50
0
% S
% Thr:
0
0
0
0
0
7
25
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
7
44
0
0
7
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
7
13
7
69
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _