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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E3
All Species:
12.12
Human Site:
T137
Identified Species:
17.78
UniProt:
Q8N5X7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5X7
NP_001128121.1
224
24441
T137
V
P
K
D
S
T
S
T
V
W
K
E
L
L
L
Chimpanzee
Pan troglodytes
XP_526229
376
41048
T289
V
P
K
D
S
T
S
T
V
W
K
E
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001084944
264
28611
T177
V
P
K
D
S
T
S
T
V
W
K
E
L
L
L
Dog
Lupus familis
XP_541806
183
20579
I106
K
E
L
L
L
A
T
I
G
E
Q
F
T
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBB5
207
22818
V121
P
K
D
S
T
S
T
V
W
K
E
L
L
L
A
Rat
Rattus norvegicus
P63074
217
25035
S124
L
N
K
Q
Q
R
R
S
D
L
D
R
F
W
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509774
252
27662
A165
V
P
K
E
S
T
A
A
V
W
K
E
L
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR08
218
24796
L131
V
P
K
E
A
S
S
L
V
W
K
E
L
L
L
Zebra Danio
Brachydanio rerio
Q66HY7
224
25384
A137
V
P
K
E
S
T
L
A
V
W
K
E
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
D168
L
N
K
S
S
K
T
D
L
D
N
L
W
L
D
Honey Bee
Apis mellifera
XP_392604
210
24074
K128
C
H
K
S
D
T
E
K
I
W
K
E
M
V
L
Nematode Worm
Caenorhab. elegans
O61955
248
27791
D122
Q
R
R
T
Q
L
L
D
H
Y
W
L
E
L
L
Sea Urchin
Strong. purpuratus
NP_001091926
211
24181
K126
V
Q
K
Q
N
T
T
K
L
W
K
E
V
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
T133
C
G
R
G
K
S
D
T
F
W
L
H
T
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FK59
221
25726
R133
F
S
K
V
V
S
A
R
F
W
E
D
L
L
L
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
I126
L
R
G
K
G
A
D
I
D
E
L
W
L
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.1
69.6
75.4
N.A.
87.9
28.1
N.A.
63
N.A.
73.2
70
N.A.
24.7
47.3
28.2
49.5
Protein Similarity:
100
54.5
72.3
78.5
N.A.
90.1
43.7
N.A.
72.2
N.A.
80.8
78.1
N.A.
44.4
64.7
42.7
66.5
P-Site Identity:
100
100
100
0
N.A.
13.3
13.3
N.A.
80
N.A.
73.3
80
N.A.
20
40
13.3
53.3
P-Site Similarity:
100
100
100
13.3
N.A.
40
26.6
N.A.
93.3
N.A.
93.3
86.6
N.A.
40
60
26.6
80
Percent
Protein Identity:
N.A.
29.4
N.A.
28.1
26.3
N.A.
Protein Similarity:
N.A.
46.8
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
26.6
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
60
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
13
13
13
0
0
0
0
0
0
7
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
7
19
7
0
13
13
13
7
7
7
0
7
7
% D
% Glu:
0
7
0
19
0
0
7
0
0
13
13
50
7
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
13
0
0
7
7
0
0
% F
% Gly:
0
7
7
7
7
0
0
0
7
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
7
0
0
0
0
0
0
% I
% Lys:
7
7
69
7
7
7
0
13
0
7
50
0
0
0
0
% K
% Leu:
19
0
7
7
7
7
13
7
13
7
13
19
57
75
75
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
13
0
0
7
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
7
38
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
0
13
13
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
13
13
0
0
7
7
7
0
0
0
7
0
7
0
% R
% Ser:
0
7
0
19
38
25
25
7
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
7
7
44
25
25
0
0
0
0
13
0
7
% T
% Val:
44
0
0
7
7
0
0
7
38
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
63
7
7
7
7
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _