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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E3
All Species:
23.03
Human Site:
T54
Identified Species:
33.78
UniProt:
Q8N5X7
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5X7
NP_001128121.1
224
24441
T54
V
P
L
H
S
S
W
T
F
W
L
D
R
S
L
Chimpanzee
Pan troglodytes
XP_526229
376
41048
C206
V
A
M
N
S
L
H
C
Y
F
K
K
Q
S
L
Rhesus Macaque
Macaca mulatta
XP_001084944
264
28611
S94
E
K
V
A
R
I
E
S
L
E
L
L
R
S
L
Dog
Lupus familis
XP_541806
183
20579
A23
Q
V
R
S
L
P
G
A
T
A
A
E
C
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBB5
207
22818
F38
P
L
H
S
P
W
T
F
W
L
D
R
S
L
P
Rat
Rattus norvegicus
P63074
217
25035
N41
Y
I
K
H
P
L
Q
N
R
W
A
L
W
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509774
252
27662
G82
E
A
A
G
N
S
G
G
P
P
V
I
Q
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR08
218
24796
T48
I
P
L
H
S
P
W
T
F
W
L
D
R
S
L
Zebra Danio
Brachydanio rerio
Q66HY7
224
25384
T54
L
P
L
H
S
P
W
T
F
W
L
D
R
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
N85
L
Y
K
H
P
L
M
N
V
W
T
L
W
Y
L
Honey Bee
Apis mellifera
XP_392604
210
24074
T45
I
P
L
Q
S
S
W
T
F
W
L
D
K
A
I
Nematode Worm
Caenorhab. elegans
O61955
248
27791
A39
H
P
L
Q
N
R
W
A
L
W
Y
L
K
A
D
Sea Urchin
Strong. purpuratus
NP_001091926
211
24181
T43
V
P
L
N
T
P
W
T
F
W
L
E
R
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
T50
H
P
L
E
H
S
W
T
F
W
F
D
N
P
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FK59
221
25726
S50
H
P
L
R
Y
K
F
S
I
W
Y
T
R
R
T
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
W43
K
H
P
L
N
T
K
W
T
L
W
Y
T
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.1
69.6
75.4
N.A.
87.9
28.1
N.A.
63
N.A.
73.2
70
N.A.
24.7
47.3
28.2
49.5
Protein Similarity:
100
54.5
72.3
78.5
N.A.
90.1
43.7
N.A.
72.2
N.A.
80.8
78.1
N.A.
44.4
64.7
42.7
66.5
P-Site Identity:
100
26.6
26.6
0
N.A.
0
13.3
N.A.
20
N.A.
86.6
86.6
N.A.
20
66.6
26.6
66.6
P-Site Similarity:
100
60
40
13.3
N.A.
6.6
13.3
N.A.
40
N.A.
93.3
93.3
N.A.
26.6
93.3
46.6
93.3
Percent
Protein Identity:
N.A.
29.4
N.A.
28.1
26.3
N.A.
Protein Similarity:
N.A.
46.8
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
53.3
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
7
7
0
0
0
13
0
7
13
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
7
32
0
0
7
% D
% Glu:
13
0
0
7
0
0
7
0
0
7
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
7
38
7
7
0
0
7
7
% F
% Gly:
0
0
0
7
0
0
13
7
0
0
0
0
0
0
0
% G
% His:
19
7
7
32
7
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
13
7
0
0
0
7
0
0
7
0
0
7
0
0
7
% I
% Lys:
7
7
13
0
0
7
7
0
0
0
7
7
13
7
0
% K
% Leu:
13
7
50
7
7
19
0
0
13
13
38
25
0
7
44
% L
% Met:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
13
19
0
0
13
0
0
0
0
7
0
0
% N
% Pro:
7
50
7
0
19
25
0
0
7
7
0
0
0
7
13
% P
% Gln:
7
0
0
13
0
0
7
0
0
0
0
0
13
0
7
% Q
% Arg:
0
0
7
7
7
7
0
0
7
0
0
7
38
7
0
% R
% Ser:
0
0
0
13
32
25
0
13
0
0
0
0
7
44
7
% S
% Thr:
0
0
0
0
7
7
7
38
13
0
7
7
7
0
7
% T
% Val:
19
7
7
0
0
0
0
0
7
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
44
7
7
63
7
0
13
0
0
% W
% Tyr:
7
7
0
0
7
0
0
0
7
0
13
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _