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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSL3 All Species: 25.45
Human Site: Y494 Identified Species: 56
UniProt: Q8N5Y2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5Y2 NP_523352.1 521 59824 Y494 F L R F L A E Y H D D F F P E
Chimpanzee Pan troglodytes XP_001144271 514 58509 Y487 F L R F L A E Y H D D F F P E
Rhesus Macaque Macaca mulatta XP_001115073 377 42807 Y351 V A A S E V H Y S T K N S Q A
Dog Lupus familis XP_548862 522 59937 Y495 F L R F L A E Y H D D F F P E
Cat Felis silvestris
Mouse Mus musculus Q9WVG9 525 60274 Y498 F L R F L A E Y H D D F F P E
Rat Rattus norvegicus Q6AYU1 323 37182 Y297 Y L H D F L K Y L A K N S A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515141 436 50284 Y409 F L R F L A E Y H D D F F P E
Chicken Gallus gallus XP_416839 522 60451 Y495 F L R F L A E Y H D D F F P E
Frog Xenopus laevis NP_001088156 355 40873 H329 L R F L A E Y H E D F F P E S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P50536 512 58834 E486 H R E W F D R E N F V N S T A
Honey Bee Apis mellifera XP_001121900 511 58651 S482 K Y L D M F L S Y L E M H R E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.4 59.5 96.9 N.A. 87.8 23.7 N.A. 72.3 84.6 55.2 N.A. N.A. 20.3 34.7 N.A. N.A.
Protein Similarity: 100 95 63.3 98.2 N.A. 93.7 38.2 N.A. 78.6 92.1 62 N.A. N.A. 38 53.1 N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 13.3 N.A. 100 100 13.3 N.A. N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 100 26.6 N.A. 100 100 20 N.A. N.A. 13.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 10 55 0 0 0 10 0 0 0 10 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 10 0 0 0 64 55 0 0 0 0 % D
% Glu: 0 0 10 0 10 10 55 10 10 0 10 0 0 10 64 % E
% Phe: 55 0 10 55 19 10 0 0 0 10 10 64 55 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 0 10 0 0 0 10 10 55 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 10 0 0 0 19 0 0 0 0 % K
% Leu: 10 64 10 10 55 10 10 0 10 10 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 28 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 10 55 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 19 55 0 0 0 10 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 10 0 0 0 10 10 0 0 0 28 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 10 % T
% Val: 10 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 0 0 0 10 73 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _