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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP16
All Species:
18.18
Human Site:
T181
Identified Species:
50
UniProt:
Q8N5Y8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5Y8
NP_060321.3
322
36383
T181
T
S
L
F
G
E
G
T
Y
L
T
S
D
L
S
Chimpanzee
Pan troglodytes
XP_001174388
308
34589
K173
G
L
H
C
H
L
N
K
T
S
L
F
G
E
G
Rhesus Macaque
Macaca mulatta
XP_001109120
322
36390
T181
T
S
L
F
G
E
G
T
Y
L
T
S
D
L
S
Dog
Lupus familis
XP_853463
411
45535
T270
T
S
L
F
G
E
G
T
Y
L
T
S
D
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMM8
322
36746
T181
T
S
L
F
G
E
G
T
Y
L
T
S
D
L
S
Rat
Rattus norvegicus
Q5U2Q4
322
36694
T181
T
S
L
F
G
E
G
T
Y
L
T
S
D
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518705
267
30307
A132
L
T
S
D
L
S
L
A
L
L
Y
S
P
H
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624248
332
37650
I188
K
S
L
F
G
K
G
I
Y
L
S
S
E
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787279
305
33629
E170
E
R
F
K
T
L
S
E
Q
Y
D
V
L
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
98.7
72.2
N.A.
90.3
89.1
N.A.
58.3
N.A.
N.A.
N.A.
N.A.
N.A.
29.8
N.A.
42.5
Protein Similarity:
100
95
99.6
74.2
N.A.
93.4
91.9
N.A.
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
50.2
N.A.
58.7
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
60
N.A.
0
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
80
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
12
0
56
0
0
% D
% Glu:
12
0
0
0
0
56
0
12
0
0
0
0
12
12
0
% E
% Phe:
0
0
12
67
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
12
0
0
0
67
0
67
0
0
0
0
0
12
0
34
% G
% His:
0
0
12
0
12
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
12
0
12
0
12
0
0
0
0
0
0
0
% K
% Leu:
12
12
67
0
12
23
12
0
12
78
12
0
12
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
67
12
0
0
12
12
0
0
12
12
78
0
0
56
% S
% Thr:
56
12
0
0
12
0
0
56
12
0
56
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
67
12
12
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _