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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM86B
All Species:
17.71
Human Site:
S220
Identified Species:
35.41
UniProt:
Q8N661
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N661
NP_776165.2
226
24352
S220
I
T
L
S
A
L
R
S
P
V
P
K
T
D
_
Chimpanzee
Pan troglodytes
XP_001135069
226
24373
S220
I
T
L
S
A
L
R
S
P
V
P
K
T
D
_
Rhesus Macaque
Macaca mulatta
XP_001096748
240
26380
S227
V
A
L
S
A
V
E
S
R
E
P
V
E
H
Y
Dog
Lupus familis
XP_854095
226
24943
S220
I
T
L
S
A
F
Q
S
R
R
L
K
T
T
_
Cat
Felis silvestris
Mouse
Mus musculus
Q497J1
226
24970
N220
L
I
L
S
A
L
R
N
P
G
L
K
T
H
_
Rat
Rattus norvegicus
NP_001103074
226
25138
S220
L
T
L
S
A
L
R
S
P
G
L
K
T
H
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507840
223
23804
R215
L
A
L
T
V
V
E
R
G
D
P
S
P
K
A
Chicken
Gallus gallus
XP_426403
237
26456
S227
I
A
L
S
A
V
E
S
R
D
E
E
D
F
K
Frog
Xenopus laevis
NP_001086666
237
26548
C227
I
A
L
S
A
V
E
C
Q
D
E
N
D
Y
R
Zebra Danio
Brachydanio rerio
NP_001013530
237
26037
C227
I
A
L
S
A
V
E
C
Q
D
A
D
T
S
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393044
231
25598
S223
I
A
L
S
A
V
G
S
K
N
N
N
N
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782851
242
26872
H233
I
A
L
S
V
V
S
H
G
H
S
I
E
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
36.6
64.1
N.A.
65.9
69
N.A.
48.6
36.7
37.1
37.1
N.A.
N.A.
35
N.A.
34.3
Protein Similarity:
100
98.6
51.6
73.8
N.A.
73.8
76.5
N.A.
61
52.7
51
52.3
N.A.
N.A.
51.9
N.A.
51.6
P-Site Identity:
100
100
33.3
57.1
N.A.
57.1
71.4
N.A.
13.3
33.3
26.6
33.3
N.A.
N.A.
33.3
N.A.
20
P-Site Similarity:
100
100
53.3
64.2
N.A.
71.4
78.5
N.A.
33.3
46.6
33.3
40
N.A.
N.A.
46.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
0
84
0
0
0
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
34
0
9
17
17
0
% D
% Glu:
0
0
0
0
0
0
42
0
0
9
17
9
17
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
9
0
17
17
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
9
0
0
0
25
0
% H
% Ile:
67
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
42
0
17
25
% K
% Leu:
25
0
100
0
0
34
0
0
0
0
25
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
9
17
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
34
0
34
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
34
9
25
9
0
0
0
0
9
% R
% Ser:
0
0
0
92
0
0
9
59
0
0
9
9
0
9
0
% S
% Thr:
0
34
0
9
0
0
0
0
0
0
0
0
50
9
0
% T
% Val:
9
0
0
0
17
59
0
0
0
17
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% _