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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM86B
All Species:
6.97
Human Site:
T12
Identified Species:
13.94
UniProt:
Q8N661
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N661
NP_776165.2
226
24352
T12
K
A
G
Q
T
L
K
T
H
C
S
A
Q
R
P
Chimpanzee
Pan troglodytes
XP_001135069
226
24373
T12
K
A
G
Q
T
L
K
T
H
C
S
A
Q
R
P
Rhesus Macaque
Macaca mulatta
XP_001096748
240
26380
P13
T
V
V
K
S
E
G
P
K
L
V
P
F
F
K
Dog
Lupus familis
XP_854095
226
24943
P12
E
E
G
L
P
G
K
P
C
F
L
V
Q
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q497J1
226
24970
T12
K
E
G
L
P
L
E
T
L
F
S
D
Q
Y
P
Rat
Rattus norvegicus
NP_001103074
226
25138
I12
K
E
G
L
S
L
E
I
L
F
S
D
Q
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507840
223
23804
L13
R
S
R
E
P
S
L
L
G
I
C
L
H
L
L
Chicken
Gallus gallus
XP_426403
237
26456
P13
C
M
V
K
S
E
G
P
K
L
V
P
F
F
K
Frog
Xenopus laevis
NP_001086666
237
26548
P13
T
V
V
K
S
E
G
P
K
L
V
P
F
F
K
Zebra Danio
Brachydanio rerio
NP_001013530
237
26037
P13
T
V
V
K
S
E
G
P
K
L
V
P
F
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393044
231
25598
I11
P
A
Q
V
L
K
S
I
G
P
K
L
V
P
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782851
242
26872
R18
V
A
K
A
V
C
P
R
L
L
P
F
I
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
36.6
64.1
N.A.
65.9
69
N.A.
48.6
36.7
37.1
37.1
N.A.
N.A.
35
N.A.
34.3
Protein Similarity:
100
98.6
51.6
73.8
N.A.
73.8
76.5
N.A.
61
52.7
51
52.3
N.A.
N.A.
51.9
N.A.
51.6
P-Site Identity:
100
100
0
26.6
N.A.
46.6
40
N.A.
0
0
0
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
40
N.A.
53.3
53.3
N.A.
20
13.3
13.3
13.3
N.A.
N.A.
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
9
0
0
0
0
0
0
0
17
0
0
0
% A
% Cys:
9
0
0
0
0
9
0
0
9
17
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% D
% Glu:
9
25
0
9
0
34
17
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
25
0
9
34
34
9
% F
% Gly:
0
0
42
0
0
9
34
0
17
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
17
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
17
0
9
0
0
9
0
0
% I
% Lys:
34
0
9
34
0
9
25
0
34
0
9
0
0
0
34
% K
% Leu:
0
0
0
25
9
34
9
9
25
42
9
17
0
9
9
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
9
0
0
0
25
0
9
42
0
9
9
34
0
9
42
% P
% Gln:
0
0
9
17
0
0
0
0
0
0
0
0
42
9
0
% Q
% Arg:
9
0
9
0
0
0
0
9
0
0
0
0
0
17
0
% R
% Ser:
0
9
0
0
42
9
9
0
0
0
34
0
0
0
0
% S
% Thr:
25
0
0
0
17
0
0
25
0
0
0
0
0
0
0
% T
% Val:
9
25
34
9
9
0
0
0
0
0
34
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _