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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM86B
All Species:
20.91
Human Site:
T190
Identified Species:
41.82
UniProt:
Q8N661
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N661
NP_776165.2
226
24352
T190
D
G
V
L
A
W
D
T
F
A
Q
P
L
P
H
Chimpanzee
Pan troglodytes
XP_001135069
226
24373
T190
D
G
V
L
A
W
D
T
F
A
Q
P
L
P
H
Rhesus Macaque
Macaca mulatta
XP_001096748
240
26380
K197
D
L
T
I
A
L
N
K
F
C
F
P
V
P
Y
Dog
Lupus familis
XP_854095
226
24943
T190
D
S
V
L
A
W
D
T
F
V
Q
P
L
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q497J1
226
24970
T190
D
G
V
L
A
W
D
T
F
V
Y
S
L
P
F
Rat
Rattus norvegicus
NP_001103074
226
25138
T190
D
G
V
L
A
W
D
T
F
V
Y
T
L
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507840
223
23804
T185
D
S
I
L
A
L
D
T
F
V
S
P
V
P
A
Chicken
Gallus gallus
XP_426403
237
26456
K197
D
L
T
I
A
V
N
K
F
C
F
P
V
P
Y
Frog
Xenopus laevis
NP_001086666
237
26548
K197
D
L
T
I
A
V
N
K
F
C
F
P
V
P
C
Zebra Danio
Brachydanio rerio
NP_001013530
237
26037
K197
D
L
T
I
A
V
N
K
F
C
F
P
V
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393044
231
25598
Y193
D
T
L
L
G
F
H
Y
F
H
T
P
L
P
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782851
242
26872
M203
D
V
V
L
A
T
N
M
F
R
S
A
I
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
36.6
64.1
N.A.
65.9
69
N.A.
48.6
36.7
37.1
37.1
N.A.
N.A.
35
N.A.
34.3
Protein Similarity:
100
98.6
51.6
73.8
N.A.
73.8
76.5
N.A.
61
52.7
51
52.3
N.A.
N.A.
51.9
N.A.
51.6
P-Site Identity:
100
100
33.3
86.6
N.A.
73.3
73.3
N.A.
53.3
33.3
33.3
40
N.A.
N.A.
40
N.A.
40
P-Site Similarity:
100
100
60
86.6
N.A.
73.3
73.3
N.A.
66.6
60
53.3
60
N.A.
N.A.
60
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
92
0
0
0
0
17
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
9
% C
% Asp:
100
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
100
0
34
0
0
0
17
% F
% Gly:
0
34
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
34
% H
% Ile:
0
0
9
34
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% K
% Leu:
0
34
9
67
0
17
0
0
0
0
0
0
50
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
42
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
75
0
100
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
17
0
0
0
0
0
0
0
0
17
9
0
0
9
% S
% Thr:
0
9
34
0
0
9
0
50
0
0
9
9
0
0
0
% T
% Val:
0
9
50
0
0
25
0
0
0
34
0
0
42
0
0
% V
% Trp:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
17
0
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _