Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM86B All Species: 15.45
Human Site: T74 Identified Species: 30.91
UniProt: Q8N661 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N661 NP_776165.2 226 24352 T74 M S P S G G Y T Q L L Q G A L
Chimpanzee Pan troglodytes XP_001135069 226 24373 T74 V S P S G G Y T Q F L Q G A L
Rhesus Macaque Macaca mulatta XP_001096748 240 26380 A68 F L L A H P S A T R I F V G L
Dog Lupus familis XP_854095 226 24943 H74 V R G G R G Y H T R L Q G A L
Cat Felis silvestris
Mouse Mus musculus Q497J1 226 24970 T74 V A P G G S S T W L L Q G A L
Rat Rattus norvegicus NP_001103074 226 25138 T74 V A P G G S Y T W L L Q G A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507840 223 23804 V68 Q E R G N P S V P W V R L G L
Chicken Gallus gallus XP_426403 237 26456 S69 L V A H R S A S R I L A G L I
Frog Xenopus laevis NP_001086666 237 26548 A68 F L V T H R C A K R I L A G L
Zebra Danio Brachydanio rerio NP_001013530 237 26037 A68 F L G A H S S A R K I L A G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393044 231 25598 S66 L S Q E Y T F S R R I L T G L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782851 242 26872 H74 L S V F P R Y H L A I L T G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.7 36.6 64.1 N.A. 65.9 69 N.A. 48.6 36.7 37.1 37.1 N.A. N.A. 35 N.A. 34.3
Protein Similarity: 100 98.6 51.6 73.8 N.A. 73.8 76.5 N.A. 61 52.7 51 52.3 N.A. N.A. 51.9 N.A. 51.6
P-Site Identity: 100 86.6 6.6 46.6 N.A. 60 66.6 N.A. 6.6 13.3 6.6 6.6 N.A. N.A. 13.3 N.A. 20
P-Site Similarity: 100 93.3 20 53.3 N.A. 73.3 80 N.A. 20 46.6 26.6 26.6 N.A. N.A. 46.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 17 0 0 9 25 0 9 0 9 17 42 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 25 0 0 9 0 0 9 0 0 9 0 9 0 0 0 % F
% Gly: 0 0 17 34 34 25 0 0 0 0 0 0 50 50 0 % G
% His: 0 0 0 9 25 0 0 17 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 42 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % K
% Leu: 25 25 9 0 0 0 0 0 9 25 50 34 9 9 92 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 34 0 9 17 0 0 9 0 0 0 0 0 0 % P
% Gln: 9 0 9 0 0 0 0 0 17 0 0 42 0 0 0 % Q
% Arg: 0 9 9 0 17 17 0 0 25 34 0 9 0 0 0 % R
% Ser: 0 34 0 17 0 34 34 17 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 9 0 9 0 34 17 0 0 0 17 0 0 % T
% Val: 34 9 17 0 0 0 0 9 0 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 17 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 42 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _