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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPSF7 All Species: 29.39
Human Site: S166 Identified Species: 64.67
UniProt: Q8N684 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N684 NP_001129512.1 471 52050 S166 P A T R Q N L S Q F E A Q A R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082435 519 57231 Q224 A T R Q N L S Q F E A Q A R K
Dog Lupus familis XP_533274 514 56498 S218 P A T R Q N L S Q F E A Q A R
Cat Felis silvestris
Mouse Mus musculus Q8BTV2 471 51993 S166 P A T R Q N L S Q F E A Q A R
Rat Rattus norvegicus Q5XI29 462 51054 S166 P A T R Q N L S Q F E A Q A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZL34 551 59341 S165 P C N K Q F L S Q F E M Q S R
Frog Xenopus laevis Q6DDW4 548 59387 S165 P C N K Q F L S Q F E M Q S R
Zebra Danio Brachydanio rerio Q6NWC6 545 58757 S165 P C N K Q S L S Q F E M Q S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSH4 652 71076 T177 Y P S K Q A L T Q F E S L Q K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501551 489 53643 T181 D A Q A K N Q T R P D V K K K
Sea Urchin Strong. purpuratus XP_782654 898 96357 N221 P Q G P P H M N Q G P P P M N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 83.2 89.4 N.A. 98.7 96.5 N.A. N.A. 44.2 43.9 44.5 N.A. 34.8 N.A. 31.2 21.8
Protein Similarity: 100 N.A. 84.3 89.8 N.A. 99.3 97.2 N.A. N.A. 56.8 56.2 58.1 N.A. 46.1 N.A. 47.4 34.5
P-Site Identity: 100 N.A. 0 100 N.A. 100 100 N.A. N.A. 60 60 60 N.A. 33.3 N.A. 13.3 13.3
P-Site Similarity: 100 N.A. 13.3 100 N.A. 100 100 N.A. N.A. 73.3 73.3 80 N.A. 66.6 N.A. 53.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 46 0 10 0 10 0 0 0 0 10 37 10 37 0 % A
% Cys: 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 73 0 0 0 0 % E
% Phe: 0 0 0 0 0 19 0 0 10 73 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 37 10 0 0 0 0 0 0 0 10 10 28 % K
% Leu: 0 0 0 0 0 10 73 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 28 0 10 0 % M
% Asn: 0 0 28 0 10 46 0 10 0 0 0 0 0 0 10 % N
% Pro: 73 10 0 10 10 0 0 0 0 10 10 10 10 0 0 % P
% Gln: 0 10 10 10 73 0 10 10 82 0 0 10 64 10 0 % Q
% Arg: 0 0 10 37 0 0 0 0 10 0 0 0 0 10 64 % R
% Ser: 0 0 10 0 0 10 10 64 0 0 0 10 0 28 0 % S
% Thr: 0 10 37 0 0 0 0 19 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _