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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPSF7 All Species: 26.06
Human Site: S330 Identified Species: 57.33
UniProt: Q8N684 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N684 NP_001129512.1 471 52050 S330 R D S G P P P S T V S E A E F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082435 519 57231 S378 R D S G P P P S T V S E A E F
Dog Lupus familis XP_533274 514 56498 S373 R D S G P P P S T V S E A E F
Cat Felis silvestris
Mouse Mus musculus Q8BTV2 471 51993 S330 R D S G P P P S T V S E A E F
Rat Rattus norvegicus Q5XI29 462 51054 S321 R D S G P L P S T V S E A E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZL34 551 59341 T407 R E M D A A R T P L S E A E F
Frog Xenopus laevis Q6DDW4 548 59387 T403 R D M D V V R T P L S E A E F
Zebra Danio Brachydanio rerio Q6NWC6 545 58757 T400 R D M D A S R T P L S E A E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSH4 652 71076 P441 P D P Q Q M G P Q L T E V E F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501551 489 53643 Q361 P P V H V N P Q M F P G L Q G
Sea Urchin Strong. purpuratus XP_782654 898 96357 P740 D R Q P S P A P Q L G E A E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 83.2 89.4 N.A. 98.7 96.5 N.A. N.A. 44.2 43.9 44.5 N.A. 34.8 N.A. 31.2 21.8
Protein Similarity: 100 N.A. 84.3 89.8 N.A. 99.3 97.2 N.A. N.A. 56.8 56.2 58.1 N.A. 46.1 N.A. 47.4 34.5
P-Site Identity: 100 N.A. 100 100 N.A. 100 93.3 N.A. N.A. 40 46.6 46.6 N.A. 26.6 N.A. 6.6 33.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 93.3 N.A. N.A. 60 60 60 N.A. 40 N.A. 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 10 10 0 0 0 0 0 82 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 73 0 28 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 91 0 91 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 91 % F
% Gly: 0 0 0 46 0 0 10 0 0 0 10 10 0 0 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 46 0 0 10 0 0 % L
% Met: 0 0 28 0 0 10 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 10 10 10 46 46 55 19 28 0 10 0 0 0 0 % P
% Gln: 0 0 10 10 10 0 0 10 19 0 0 0 0 10 0 % Q
% Arg: 73 10 0 0 0 0 28 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 46 0 10 10 0 46 0 0 73 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 28 46 0 10 0 0 0 0 % T
% Val: 0 0 10 0 19 10 0 0 0 46 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _