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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEFB123
All Species:
8.18
Human Site:
Y45
Identified Species:
45
UniProt:
Q8N688
Number Species:
4
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N688
NP_697019.1
67
8105
Y45
K
K
E
R
V
Y
V
Y
C
I
N
N
K
M
C
Chimpanzee
Pan troglodytes
NP_001123239
76
8493
K45
E
V
Y
Y
I
L
C
K
T
E
A
K
C
C
V
Rhesus Macaque
Macaca mulatta
Q5J5D0
67
8032
Y45
K
K
E
R
V
Y
V
Y
C
L
N
N
K
M
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3U4
67
7737
Y45
R
K
E
S
V
Y
V
Y
C
T
N
G
K
M
C
Rat
Rattus norvegicus
Q32ZG2
75
8689
F55
K
K
E
I
F
H
I
F
C
G
T
Q
F
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.4
95.5
N.A.
N.A.
76.1
32
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
53.9
100
N.A.
N.A.
85
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
N.A.
N.A.
73.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
N.A.
N.A.
80
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
20
0
80
0
0
0
20
20
80
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
80
0
0
0
0
0
0
20
0
0
0
0
0
% E
% Phe:
0
0
0
0
20
0
0
20
0
0
0
0
20
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
20
0
20
0
0
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
20
0
20
0
0
20
0
0
0
0
0
% I
% Lys:
60
80
0
0
0
0
0
20
0
0
0
20
60
0
0
% K
% Leu:
0
0
0
0
0
20
0
0
0
20
0
0
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
60
40
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% Q
% Arg:
20
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
20
20
20
0
0
0
0
% T
% Val:
0
20
0
0
60
0
60
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
20
0
60
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _