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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESX1
All Species:
6.97
Human Site:
S161
Identified Species:
25.56
UniProt:
Q8N693
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N693
NP_703149.1
406
44297
S161
L
E
N
F
F
D
E
S
Q
Y
P
D
V
V
A
Chimpanzee
Pan troglodytes
A2T711
184
20085
K63
S
R
E
E
L
A
A
K
V
H
L
P
E
V
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PVY0
228
25826
T107
S
S
M
K
L
H
D
T
P
M
L
S
F
N
R
Frog
Xenopus laevis
Q0P031
344
38194
A172
L
E
K
S
F
N
E
A
H
Y
P
D
V
Y
A
Zebra Danio
Brachydanio rerio
O42356
330
36917
S159
L
E
R
A
F
E
K
S
H
Y
P
D
V
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119902
304
33669
M145
L
G
R
D
T
N
F
M
H
V
E
Q
S
G
V
Nematode Worm
Caenorhab. elegans
P41935
344
38253
S158
L
E
K
A
F
Q
D
S
H
Y
P
D
I
Y
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.6
21.6
25.1
N.A.
N.A.
24.6
20.9
N.A.
Protein Similarity:
100
31
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
34.7
34.2
38.1
N.A.
N.A.
39.4
34.7
N.A.
P-Site Identity:
100
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
60
53.3
N.A.
N.A.
6.6
53.3
N.A.
P-Site Similarity:
100
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
73.3
73.3
N.A.
N.A.
13.3
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
29
0
15
15
15
0
0
0
0
0
0
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
15
29
0
0
0
0
58
0
0
0
% D
% Glu:
0
58
15
15
0
15
29
0
0
0
15
0
15
0
0
% E
% Phe:
0
0
0
15
58
0
15
0
0
0
0
0
15
0
0
% F
% Gly:
0
15
0
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
15
0
0
58
15
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% I
% Lys:
0
0
29
15
0
0
15
15
0
0
0
0
0
0
0
% K
% Leu:
72
0
0
0
29
0
0
0
0
0
29
0
0
0
0
% L
% Met:
0
0
15
0
0
0
0
15
0
15
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
29
0
0
0
0
0
0
0
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
15
0
58
15
0
0
0
% P
% Gln:
0
0
0
0
0
15
0
0
15
0
0
15
0
0
0
% Q
% Arg:
0
15
29
0
0
0
0
0
0
0
0
0
0
0
29
% R
% Ser:
29
15
0
15
0
0
0
43
0
0
0
15
15
0
15
% S
% Thr:
0
0
0
0
15
0
0
15
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
15
15
0
0
43
29
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
58
0
0
0
43
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _