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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC15A4 All Species: 17.88
Human Site: S270 Identified Species: 28.1
UniProt: Q8N697 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N697 NP_663623.1 577 62034 S270 I L T Y S C C S Q K R S G E R
Chimpanzee Pan troglodytes XP_001137177 578 61971 S271 I L T Y S C C S Q K R S G E R
Rhesus Macaque Macaca mulatta XP_001084703 580 62690 P274 L A L Q N C C P Q L W Q R H L
Dog Lupus familis XP_852542 566 61087 P263 I L A Y S C R P Q K R I G E H
Cat Felis silvestris
Mouse Mus musculus Q91W98 574 62237 S273 I L T Y S C C S Q R G G Q R R
Rat Rattus norvegicus O09014 572 61930 S271 I L T Y S C C S Q R G G Q R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508474 657 71951 S322 I L A Y S C C S Q K R G P R P
Chicken Gallus gallus XP_415099 492 54115 P209 G Q G V L Q Q P R K Q S L F E
Frog Xenopus laevis Q68F72 569 63068 S277 I L A Y F C C S R K H T R E N
Zebra Danio Brachydanio rerio NP_957251 428 46870 S145 Y C R P A I Y S G L V L V A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783351 614 68101 R289 I I A Q A F K R R K M R K E I
Poplar Tree Populus trichocarpa XP_002315835 584 64173 K277 V L V A S F H K W N L E V P L
Maize Zea mays NP_001146682 587 64502 K279 V I V A S L R K W N V P V P E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFB8 570 63290 K258 V I V A S C R K S K V K I P E
Baker's Yeast Sacchar. cerevisiae P32901 601 68025 K303 I Q R P I G D K V I A K S F K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 45.8 84.7 N.A. 87.1 87.6 N.A. 53.7 68.1 71 39.6 N.A. N.A. N.A. N.A. 40.3
Protein Similarity: 100 99.6 62.2 89.7 N.A. 93 93 N.A. 62.2 74.5 80.2 49.9 N.A. N.A. N.A. N.A. 55.7
P-Site Identity: 100 100 20 66.6 N.A. 66.6 66.6 N.A. 66.6 13.3 53.3 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 33.3 66.6 N.A. 73.3 73.3 N.A. 66.6 26.6 66.6 13.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 30.1 28.6 N.A. 28.2 22.6 N.A.
Protein Similarity: 47.9 48 N.A. 48.3 41.1 N.A.
P-Site Identity: 13.3 6.6 N.A. 20 6.6 N.A.
P-Site Similarity: 20 20 N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 27 20 14 0 0 0 0 0 7 0 0 7 0 % A
% Cys: 0 7 0 0 0 60 47 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 0 34 20 % E
% Phe: 0 0 0 0 7 14 0 0 0 0 0 0 0 14 0 % F
% Gly: 7 0 7 0 0 7 0 0 7 0 14 20 20 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 7 0 0 7 7 % H
% Ile: 60 20 0 0 7 7 0 0 0 7 0 7 7 0 7 % I
% Lys: 0 0 0 0 0 0 7 27 0 54 0 14 7 0 7 % K
% Leu: 7 54 7 0 7 7 0 0 0 14 7 7 7 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 14 0 0 0 0 7 % N
% Pro: 0 0 0 14 0 0 0 20 0 0 0 7 7 20 7 % P
% Gln: 0 14 0 14 0 7 7 0 47 0 7 7 14 0 0 % Q
% Arg: 0 0 14 0 0 0 20 7 20 14 27 7 14 20 27 % R
% Ser: 0 0 0 0 60 0 0 47 7 0 0 20 7 0 0 % S
% Thr: 0 0 27 0 0 0 0 0 0 0 0 7 0 0 0 % T
% Val: 20 0 20 7 0 0 0 0 7 0 20 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 14 0 7 0 0 0 0 % W
% Tyr: 7 0 0 47 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _