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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A4
All Species:
8.48
Human Site:
S274
Identified Species:
13.33
UniProt:
Q8N697
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N697
NP_663623.1
577
62034
S274
S
C
C
S
Q
K
R
S
G
E
R
Q
S
N
G
Chimpanzee
Pan troglodytes
XP_001137177
578
61971
S275
S
C
C
S
Q
K
R
S
G
E
R
Q
S
N
G
Rhesus Macaque
Macaca mulatta
XP_001084703
580
62690
Q278
N
C
C
P
Q
L
W
Q
R
H
L
A
R
C
S
Dog
Lupus familis
XP_852542
566
61087
I267
S
C
R
P
Q
K
R
I
G
E
H
S
Q
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91W98
574
62237
G277
S
C
C
S
Q
R
G
G
Q
R
R
S
G
E
G
Rat
Rattus norvegicus
O09014
572
61930
G275
S
C
C
S
Q
R
G
G
Q
R
R
S
G
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508474
657
71951
G326
S
C
C
S
Q
K
R
G
P
R
P
T
G
R
G
Chicken
Gallus gallus
XP_415099
492
54115
S213
L
Q
Q
P
R
K
Q
S
L
F
E
M
A
K
L
Frog
Xenopus laevis
Q68F72
569
63068
T281
F
C
C
S
R
K
H
T
R
E
N
T
R
N
I
Zebra Danio
Brachydanio rerio
NP_957251
428
46870
L149
A
I
Y
S
G
L
V
L
V
A
L
G
V
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783351
614
68101
R293
A
F
K
R
R
K
M
R
K
E
I
S
N
K
R
Poplar Tree
Populus trichocarpa
XP_002315835
584
64173
E281
S
F
H
K
W
N
L
E
V
P
L
D
S
S
L
Maize
Zea mays
NP_001146682
587
64502
P283
S
L
R
K
W
N
V
P
V
P
E
D
S
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFB8
570
63290
K262
S
C
R
K
S
K
V
K
I
P
E
D
E
S
L
Baker's Yeast
Sacchar. cerevisiae
P32901
601
68025
K307
I
G
D
K
V
I
A
K
S
F
K
V
C
W
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
45.8
84.7
N.A.
87.1
87.6
N.A.
53.7
68.1
71
39.6
N.A.
N.A.
N.A.
N.A.
40.3
Protein Similarity:
100
99.6
62.2
89.7
N.A.
93
93
N.A.
62.2
74.5
80.2
49.9
N.A.
N.A.
N.A.
N.A.
55.7
P-Site Identity:
100
100
20
53.3
N.A.
46.6
46.6
N.A.
53.3
13.3
40
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
26.6
60
N.A.
53.3
53.3
N.A.
53.3
33.3
53.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
30.1
28.6
N.A.
28.2
22.6
N.A.
Protein Similarity:
47.9
48
N.A.
48.3
41.1
N.A.
P-Site Identity:
13.3
13.3
N.A.
20
0
N.A.
P-Site Similarity:
20
20
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
0
7
0
0
7
0
7
7
0
7
% A
% Cys:
0
60
47
0
0
0
0
0
0
0
0
0
7
7
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
20
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
7
0
34
20
0
7
14
0
% E
% Phe:
7
14
0
0
0
0
0
0
0
14
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
0
14
20
20
0
0
7
20
7
40
% G
% His:
0
0
7
0
0
0
7
0
0
7
7
0
0
0
0
% H
% Ile:
7
7
0
0
0
7
0
7
7
0
7
0
0
0
14
% I
% Lys:
0
0
7
27
0
54
0
14
7
0
7
0
0
14
0
% K
% Leu:
7
7
0
0
0
14
7
7
7
0
20
0
0
0
27
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
0
0
14
0
0
0
0
7
0
7
20
0
% N
% Pro:
0
0
0
20
0
0
0
7
7
20
7
0
0
0
0
% P
% Gln:
0
7
7
0
47
0
7
7
14
0
0
14
7
0
0
% Q
% Arg:
0
0
20
7
20
14
27
7
14
20
27
0
14
7
7
% R
% Ser:
60
0
0
47
7
0
0
20
7
0
0
27
27
27
7
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
14
0
0
0
% T
% Val:
0
0
0
0
7
0
20
0
20
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
14
0
7
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _