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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC15A4 All Species: 12.73
Human Site: S4 Identified Species: 20
UniProt: Q8N697 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N697 NP_663623.1 577 62034 S4 _ _ _ _ M E G S G G G A G E R
Chimpanzee Pan troglodytes XP_001137177 578 61971 S4 _ _ _ _ M E G S G G G A G E R
Rhesus Macaque Macaca mulatta XP_001084703 580 62690 Q9 P A P R T R E Q P R V P G E R
Dog Lupus familis XP_852542 566 61087 A4 _ _ _ _ M E G A A G E R A P L
Cat Felis silvestris
Mouse Mus musculus Q91W98 574 62237 S11 E R A P L L G S R R P A V S A
Rat Rattus norvegicus O09014 572 61930 A18 S R R A A A A A G V F A G R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508474 657 71951 V13 G A K R V L G V D P I C G D I
Chicken Gallus gallus XP_415099 492 54115
Frog Xenopus laevis Q68F72 569 63068 S10 S R D P S E R S P L L G G R S
Zebra Danio Brachydanio rerio NP_957251 428 46870
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783351 614 68101 S13 D E R R P L I S R T I S E D G
Poplar Tree Populus trichocarpa XP_002315835 584 64173 N34 G D G S V D I N G N P V L K Q
Maize Zea mays NP_001146682 587 64502 T28 E S N Q V V Y T G D G S V D F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFB8 570 63290 T13 D I Y T K D G T L D I H K K P
Baker's Yeast Sacchar. cerevisiae P32901 601 68025 S9 L N H P S Q G S D D A Q D E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 45.8 84.7 N.A. 87.1 87.6 N.A. 53.7 68.1 71 39.6 N.A. N.A. N.A. N.A. 40.3
Protein Similarity: 100 99.6 62.2 89.7 N.A. 93 93 N.A. 62.2 74.5 80.2 49.9 N.A. N.A. N.A. N.A. 55.7
P-Site Identity: 100 100 20 36.3 N.A. 20 26.6 N.A. 13.3 0 20 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 20 45.4 N.A. 26.6 33.3 N.A. 33.3 0 20 0 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 30.1 28.6 N.A. 28.2 22.6 N.A.
Protein Similarity: 47.9 48 N.A. 48.3 41.1 N.A.
P-Site Identity: 6.6 13.3 N.A. 6.6 20 N.A.
P-Site Similarity: 53.3 40 N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 7 7 7 7 7 14 7 0 7 27 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 14 7 7 0 0 14 0 0 14 20 0 0 7 20 0 % D
% Glu: 14 7 0 0 0 27 7 0 0 0 7 0 7 27 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % F
% Gly: 14 0 7 0 0 0 47 0 34 20 20 7 40 0 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 7 0 0 0 0 14 0 0 0 20 0 0 0 7 % I
% Lys: 0 0 7 0 7 0 0 0 0 0 0 0 7 14 7 % K
% Leu: 7 0 0 0 7 20 0 0 7 7 7 0 7 0 7 % L
% Met: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 0 7 0 7 0 0 0 0 0 % N
% Pro: 7 0 7 20 7 0 0 0 14 7 14 7 0 7 7 % P
% Gln: 0 0 0 7 0 7 0 7 0 0 0 7 0 0 7 % Q
% Arg: 0 20 14 20 0 7 7 0 14 14 0 7 0 14 27 % R
% Ser: 14 7 0 7 14 0 0 40 0 0 0 14 0 7 7 % S
% Thr: 0 0 0 7 7 0 0 14 0 7 0 0 0 0 0 % T
% Val: 0 0 0 0 20 7 0 7 0 7 7 7 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 20 20 20 20 0 0 0 0 0 0 0 0 0 0 0 % _