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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC15A4 All Species: 13.03
Human Site: S401 Identified Species: 20.48
UniProt: Q8N697 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N697 NP_663623.1 577 62034 S401 R H G L L P S S L K R I A V G
Chimpanzee Pan troglodytes XP_001137177 578 61971 S402 R H G L L P S S L K R I A V G
Rhesus Macaque Macaca mulatta XP_001084703 580 62690 R399 L I D P L L L R C K L L P S A
Dog Lupus familis XP_852542 566 61087 L390 P I L R R H G L L P S S L K R
Cat Felis silvestris
Mouse Mus musculus Q91W98 574 62237 L398 P V L R R H G L L P S S L K R
Rat Rattus norvegicus O09014 572 61930 L396 P V L R R H G L L P S S L K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508474 657 71951 S451 R N G L L P S S L K R I A V G
Chicken Gallus gallus XP_415099 492 54115 L317 V L K R N G L L P S S L K R I
Frog Xenopus laevis Q68F72 569 63068 L393 D K L V D P F L K K R G L L P
Zebra Danio Brachydanio rerio NP_957251 428 46870 A253 M F R I L G S A L C G R G P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783351 614 68101 G423 L F Y R I F F G M L F S M L S
Poplar Tree Populus trichocarpa XP_002315835 584 64173 S400 L S S F D V I S V I C W V P I
Maize Zea mays NP_001146682 587 64502 T397 I P P A S L S T F D T L S V I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFB8 570 63290 S376 K I P S A S L S L F D T L S V
Baker's Yeast Sacchar. cerevisiae P32901 601 68025 T416 Y P F I R R Y T P L K P I T K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 45.8 84.7 N.A. 87.1 87.6 N.A. 53.7 68.1 71 39.6 N.A. N.A. N.A. N.A. 40.3
Protein Similarity: 100 99.6 62.2 89.7 N.A. 93 93 N.A. 62.2 74.5 80.2 49.9 N.A. N.A. N.A. N.A. 55.7
P-Site Identity: 100 100 13.3 6.6 N.A. 6.6 6.6 N.A. 93.3 0 20 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 20 6.6 N.A. 6.6 6.6 N.A. 100 6.6 33.3 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 30.1 28.6 N.A. 28.2 22.6 N.A.
Protein Similarity: 47.9 48 N.A. 48.3 41.1 N.A.
P-Site Identity: 6.6 13.3 N.A. 13.3 0 N.A.
P-Site Similarity: 13.3 33.3 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 0 7 0 0 0 0 20 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 7 7 0 0 0 0 % C
% Asp: 7 0 7 0 14 0 0 0 0 7 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 14 7 7 0 7 14 0 7 7 7 0 0 0 0 % F
% Gly: 0 0 20 0 0 14 20 7 0 0 7 7 7 0 20 % G
% His: 0 14 0 0 0 20 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 20 0 14 7 0 7 0 0 7 0 20 7 0 20 % I
% Lys: 7 7 7 0 0 0 0 0 7 34 7 0 7 20 14 % K
% Leu: 20 7 27 20 34 14 20 34 54 14 7 20 34 14 0 % L
% Met: 7 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % M
% Asn: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 20 14 14 7 0 27 0 0 14 20 0 7 7 14 7 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 20 0 7 34 27 7 0 7 0 0 27 7 0 7 20 % R
% Ser: 0 7 7 7 7 7 34 34 0 7 27 27 7 14 7 % S
% Thr: 0 0 0 0 0 0 0 14 0 0 7 7 0 7 0 % T
% Val: 7 14 0 7 0 7 0 0 7 0 0 0 7 27 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 7 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _