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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC15A4 All Species: 6.67
Human Site: Y557 Identified Species: 10.48
UniProt: Q8N697 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N697 NP_663623.1 577 62034 Y557 F L I I S V K Y D H H R D H Q
Chimpanzee Pan troglodytes XP_001137177 578 61971 Y558 F L I I S V K Y D H H R D H Q
Rhesus Macaque Macaca mulatta XP_001084703 580 62690 F555 Q A V T A L L F V W I A G R Y
Dog Lupus familis XP_852542 566 61087 V546 T L L L F L I V S V R Y D R Q
Cat Felis silvestris
Mouse Mus musculus Q91W98 574 62237 V554 T L L L F L I V S V K Y D R Q
Rat Rattus norvegicus O09014 572 61930 V552 T L L L F L I V S V K Y D R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508474 657 71951 A607 P L E T I E P A R A G C R S P
Chicken Gallus gallus XP_415099 492 54115 S473 L L L F L I V S V K Y D H Q K
Frog Xenopus laevis Q68F72 569 63068 L549 A V Q A A T L L L F L I I S V
Zebra Danio Brachydanio rerio NP_957251 428 46870 L409 V A G W S Y I L C S R S T Y M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783351 614 68101 V579 F M Y N R G N V M N S H P G S
Poplar Tree Populus trichocarpa XP_002315835 584 64173 Y556 L N E G H L D Y F F W L L A G
Maize Zea mays NP_001146682 587 64502 E553 W I P D N L N E G H L D Y F F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFB8 570 63290 N532 W I A K N L N N G H L D Y F F
Baker's Yeast Sacchar. cerevisiae P32901 601 68025 E572 M D Y E E E D E F D L N P I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 45.8 84.7 N.A. 87.1 87.6 N.A. 53.7 68.1 71 39.6 N.A. N.A. N.A. N.A. 40.3
Protein Similarity: 100 99.6 62.2 89.7 N.A. 93 93 N.A. 62.2 74.5 80.2 49.9 N.A. N.A. N.A. N.A. 55.7
P-Site Identity: 100 100 0 20 N.A. 20 20 N.A. 6.6 6.6 0 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 26.6 40 N.A. 40 40 N.A. 6.6 33.3 13.3 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 30.1 28.6 N.A. 28.2 22.6 N.A.
Protein Similarity: 47.9 48 N.A. 48.3 41.1 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: 13.3 33.3 N.A. 33.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 7 7 14 0 0 7 0 7 0 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % C
% Asp: 0 7 0 7 0 0 14 0 14 7 0 20 34 0 0 % D
% Glu: 0 0 14 7 7 14 0 14 0 0 0 0 0 0 0 % E
% Phe: 20 0 0 7 20 0 0 7 14 14 0 0 0 14 14 % F
% Gly: 0 0 7 7 0 7 0 0 14 0 7 0 7 7 7 % G
% His: 0 0 0 0 7 0 0 0 0 27 14 7 7 14 0 % H
% Ile: 0 14 14 14 7 7 27 0 0 0 7 7 7 7 0 % I
% Lys: 0 0 0 7 0 0 14 0 0 7 14 0 0 0 7 % K
% Leu: 14 47 27 20 7 47 14 14 7 0 27 7 7 0 0 % L
% Met: 7 7 0 0 0 0 0 0 7 0 0 0 0 0 7 % M
% Asn: 0 7 0 7 14 0 20 7 0 7 0 7 0 0 0 % N
% Pro: 7 0 7 0 0 0 7 0 0 0 0 0 14 0 7 % P
% Gln: 7 0 7 0 0 0 0 0 0 0 0 0 0 7 34 % Q
% Arg: 0 0 0 0 7 0 0 0 7 0 14 14 7 27 0 % R
% Ser: 0 0 0 0 20 0 0 7 20 7 7 7 0 14 14 % S
% Thr: 20 0 0 14 0 7 0 0 0 0 0 0 7 0 0 % T
% Val: 7 7 7 0 0 14 7 27 14 20 0 0 0 0 7 % V
% Trp: 14 0 0 7 0 0 0 0 0 7 7 0 0 0 0 % W
% Tyr: 0 0 14 0 0 7 0 20 0 0 7 20 14 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _