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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN19
All Species:
9.09
Human Site:
Y159
Identified Species:
22.22
UniProt:
Q8N6F1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N6F1
NP_001116867.1
224
23229
Y159
S
T
P
V
N
A
R
Y
E
F
G
P
A
L
F
Chimpanzee
Pan troglodytes
XP_001173041
182
18841
V118
N
P
I
A
K
G
R
V
A
I
A
G
G
A
L
Rhesus Macaque
Macaca mulatta
XP_001107265
211
22494
D147
Y
G
H
Q
I
V
T
D
F
Y
N
P
L
I
P
Dog
Lupus familis
XP_848612
302
31312
E238
Y
A
T
L
V
T
Q
E
F
F
N
P
S
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET38
224
23325
Y159
S
T
P
V
N
A
R
Y
E
F
G
P
A
L
F
Rat
Rattus norvegicus
Q5QT56
224
23297
Y159
S
T
P
V
N
A
R
Y
E
F
G
P
A
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514981
288
29974
G159
S
T
P
L
N
A
R
G
S
W
G
G
A
V
F
Chicken
Gallus gallus
NP_001013629
211
22608
A147
Y
G
N
R
V
A
R
A
F
Y
D
P
F
T
P
Frog
Xenopus laevis
NP_001088886
221
23846
A157
N
P
N
T
P
V
N
A
R
Y
E
F
G
S
A
Zebra Danio
Brachydanio rerio
Q9YH92
215
22846
P151
I
I
R
D
F
Y
N
P
F
T
P
V
N
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.3
52.2
66.2
N.A.
95.5
95
N.A.
60.7
55.7
74.5
46.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.3
69.1
67.8
N.A.
96.8
96.4
N.A.
67
71.4
84.8
66
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
13.3
N.A.
100
100
N.A.
60
20
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
20
33.3
N.A.
100
100
N.A.
80
26.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
50
0
20
10
0
10
0
40
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
30
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
40
40
0
10
10
0
40
% F
% Gly:
0
20
0
0
0
10
0
10
0
0
40
20
20
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
10
0
10
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
20
0
0
0
0
0
0
0
0
10
30
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
20
0
40
0
20
0
0
0
20
0
10
0
0
% N
% Pro:
0
20
40
0
10
0
0
10
0
0
10
60
0
0
30
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
60
0
10
0
0
0
0
0
0
% R
% Ser:
40
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% S
% Thr:
0
40
10
10
0
10
10
0
0
10
0
0
0
30
0
% T
% Val:
0
0
0
30
20
20
0
10
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
30
0
0
0
0
10
0
30
0
30
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _