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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGAP2
All Species:
21.21
Human Site:
S139
Identified Species:
38.89
UniProt:
Q8N6H7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N6H7
NP_115765.2
521
56720
S139
D
L
W
I
D
N
M
S
S
A
V
P
N
H
S
Chimpanzee
Pan troglodytes
XP_001166532
521
56693
S139
D
L
W
I
D
N
M
S
S
A
V
P
N
H
S
Rhesus Macaque
Macaca mulatta
XP_001110019
522
56698
S140
D
L
W
I
D
N
I
S
S
A
V
P
N
H
S
Dog
Lupus familis
XP_540747
520
56841
S139
D
L
W
I
D
N
V
S
S
A
P
S
H
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99K28
520
56580
M138
T
D
L
W
I
D
S
M
N
S
A
P
S
H
S
Rat
Rattus norvegicus
Q3MID3
520
56538
M138
T
D
L
W
I
D
N
M
N
S
A
P
S
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513767
520
56332
S139
D
P
W
I
E
S
V
S
A
V
P
G
H
S
P
Chicken
Gallus gallus
Q5F413
428
46296
R91
M
G
N
G
K
A
N
R
L
Y
E
A
F
L
P
Frog
Xenopus laevis
NP_001087396
527
57524
N139
D
L
W
I
D
G
M
N
S
T
L
V
P
P
A
Zebra Danio
Brachydanio rerio
NP_001032507
536
58567
S139
D
L
W
I
D
S
S
S
C
A
Q
P
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09531
529
57893
T141
Q
L
I
I
D
T
V
T
H
A
E
E
K
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIQ0
402
43532
T65
H
I
S
F
V
R
S
T
N
L
D
S
W
S
P
Baker's Yeast
Sacchar. cerevisiae
P38682
493
55075
D149
E
L
V
L
N
G
Q
D
S
S
D
S
P
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
93.4
N.A.
92.5
93
N.A.
86.3
20.1
72.8
70.3
N.A.
N.A.
N.A.
34.5
N.A.
Protein Similarity:
100
99.8
98.8
96.7
N.A.
96.9
97.1
N.A.
91.7
37
82.9
83.9
N.A.
N.A.
N.A.
54
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
20
20
N.A.
26.6
0
46.6
53.3
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
46.6
46.6
N.A.
60
0
66.6
66.6
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.7
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.8
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
47
16
8
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
54
16
0
0
54
16
0
8
0
0
16
0
0
0
8
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
16
8
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
8
0
16
0
0
0
0
0
8
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
16
39
0
% H
% Ile:
0
8
8
62
16
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
62
16
8
0
0
0
0
8
8
8
0
0
16
0
% L
% Met:
8
0
0
0
0
0
24
16
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
31
16
8
24
0
0
0
24
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
16
47
16
24
31
% P
% Gln:
8
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
16
24
47
47
24
0
24
24
24
39
% S
% Thr:
16
0
0
0
0
8
0
16
0
8
0
0
0
0
0
% T
% Val:
0
0
8
0
8
0
24
0
0
8
24
8
0
0
8
% V
% Trp:
0
0
54
16
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _