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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGAP2
All Species:
19.7
Human Site:
S172
Identified Species:
36.11
UniProt:
Q8N6H7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N6H7
NP_115765.2
521
56720
S172
D
A
P
A
T
E
P
S
G
T
Q
Q
P
A
P
Chimpanzee
Pan troglodytes
XP_001166532
521
56693
S172
D
A
P
A
T
E
P
S
G
T
Q
Q
P
A
P
Rhesus Macaque
Macaca mulatta
XP_001110019
522
56698
S173
D
A
P
A
T
E
P
S
G
T
Q
Q
P
A
P
Dog
Lupus familis
XP_540747
520
56841
E172
V
Q
A
P
D
P
A
E
T
Q
Q
L
T
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99K28
520
56580
S171
D
T
A
A
T
D
P
S
G
T
Q
Q
P
A
L
Rat
Rattus norvegicus
Q3MID3
520
56538
S171
D
T
A
A
T
D
P
S
G
T
Q
Q
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513767
520
56332
P172
D
V
P
A
A
E
P
P
Q
A
A
E
P
Q
Q
Chicken
Gallus gallus
Q5F413
428
46296
M124
K
Y
E
K
K
K
Y
M
D
R
S
I
D
I
N
Frog
Xenopus laevis
NP_001087396
527
57524
T172
E
A
T
P
A
S
E
T
T
S
T
T
I
T
T
Zebra Danio
Brachydanio rerio
NP_001032507
536
58567
T172
D
M
A
S
P
S
L
T
D
Q
N
G
A
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09531
529
57893
I174
S
L
S
S
D
A
Y
I
A
D
H
K
S
E
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIQ0
402
43532
G98
K
Q
H
G
W
N
D
G
G
K
I
E
A
K
Y
Baker's Yeast
Sacchar. cerevisiae
P38682
493
55075
S182
F
S
N
W
Q
K
P
S
S
N
S
S
S
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
93.4
N.A.
92.5
93
N.A.
86.3
20.1
72.8
70.3
N.A.
N.A.
N.A.
34.5
N.A.
Protein Similarity:
100
99.8
98.8
96.7
N.A.
96.9
97.1
N.A.
91.7
37
82.9
83.9
N.A.
N.A.
N.A.
54
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
73.3
73.3
N.A.
40
0
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
80
80
N.A.
46.6
6.6
26.6
20
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.7
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.8
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
31
47
16
8
8
0
8
8
8
0
16
39
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
0
0
16
16
8
0
16
8
0
0
8
0
8
% D
% Glu:
8
0
8
0
0
31
8
8
0
0
0
16
0
16
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
47
0
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
8
8
8
0
% I
% Lys:
16
0
0
8
8
16
0
0
0
8
0
8
0
16
0
% K
% Leu:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
24
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
8
8
0
0
0
16
% N
% Pro:
0
0
31
16
8
8
54
8
0
0
0
0
47
8
24
% P
% Gln:
0
16
0
0
8
0
0
0
8
16
47
39
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
8
8
16
0
16
0
47
8
8
16
8
16
0
8
% S
% Thr:
0
16
8
0
39
0
0
16
16
39
8
8
8
8
8
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
16
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _