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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGAP2
All Species:
13.64
Human Site:
S180
Identified Species:
25
UniProt:
Q8N6H7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N6H7
NP_115765.2
521
56720
S180
G
T
Q
Q
P
A
P
S
T
E
S
S
G
L
A
Chimpanzee
Pan troglodytes
XP_001166532
521
56693
S180
G
T
Q
Q
P
A
P
S
T
E
S
S
G
L
A
Rhesus Macaque
Macaca mulatta
XP_001110019
522
56698
S181
G
T
Q
Q
P
A
P
S
A
E
S
S
G
L
A
Dog
Lupus familis
XP_540747
520
56841
T180
T
Q
Q
L
T
P
S
T
E
I
S
S
L
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99K28
520
56580
P179
G
T
Q
Q
P
A
L
P
S
E
S
S
S
L
A
Rat
Rattus norvegicus
Q3MID3
520
56538
P179
G
T
Q
Q
P
A
L
P
S
E
S
S
S
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513767
520
56332
P180
Q
A
A
E
P
Q
Q
P
A
E
N
S
T
P
G
Chicken
Gallus gallus
Q5F413
428
46296
T132
D
R
S
I
D
I
N
T
F
R
K
E
K
D
D
Frog
Xenopus laevis
NP_001087396
527
57524
E180
T
S
T
T
I
T
T
E
T
R
S
I
S
A
L
Zebra Danio
Brachydanio rerio
NP_001032507
536
58567
V180
D
Q
N
G
A
E
N
V
N
P
Q
L
A
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09531
529
57893
S182
A
D
H
K
S
E
D
S
T
H
G
P
S
V
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIQ0
402
43532
T106
G
K
I
E
A
K
Y
T
S
R
A
A
D
M
Y
Baker's Yeast
Sacchar. cerevisiae
P38682
493
55075
N190
S
N
S
S
S
K
L
N
V
N
T
G
S
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
93.4
N.A.
92.5
93
N.A.
86.3
20.1
72.8
70.3
N.A.
N.A.
N.A.
34.5
N.A.
Protein Similarity:
100
99.8
98.8
96.7
N.A.
96.9
97.1
N.A.
91.7
37
82.9
83.9
N.A.
N.A.
N.A.
54
N.A.
P-Site Identity:
100
100
93.3
20
N.A.
73.3
73.3
N.A.
20
0
13.3
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
80
80
N.A.
33.3
6.6
20
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.7
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.8
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
16
39
0
0
16
0
8
8
8
16
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
8
0
0
8
0
8
0
0
0
0
0
8
8
16
% D
% Glu:
0
0
0
16
0
16
0
8
8
47
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
47
0
0
8
0
0
0
0
0
0
8
8
24
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
8
8
8
0
0
0
8
0
8
0
0
0
% I
% Lys:
0
8
0
8
0
16
0
0
0
0
8
0
8
0
0
% K
% Leu:
0
0
0
8
0
0
24
0
0
0
0
8
8
47
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
8
0
0
0
16
8
8
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
47
8
24
24
0
8
0
8
0
8
0
% P
% Gln:
8
16
47
39
0
8
8
0
0
0
8
0
0
8
8
% Q
% Arg:
0
8
0
0
0
0
0
0
0
24
0
0
0
0
0
% R
% Ser:
8
8
16
8
16
0
8
31
24
0
54
54
39
0
8
% S
% Thr:
16
39
8
8
8
8
8
24
31
0
8
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _