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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARFGAP2 All Species: 27.58
Human Site: S210 Identified Species: 50.56
UniProt: Q8N6H7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N6H7 NP_115765.2 521 56720 S210 K A S L E L K S S I I G K K K
Chimpanzee Pan troglodytes XP_001166532 521 56693 S210 K A S L E L K S S I I G K K K
Rhesus Macaque Macaca mulatta XP_001110019 522 56698 S211 K A S L E L K S S I I G K K K
Dog Lupus familis XP_540747 520 56841 S210 A S L E P R T S L I G K K K P
Cat Felis silvestris
Mouse Mus musculus Q99K28 520 56580 S209 Q A S L E L K S S I I G K K K
Rat Rattus norvegicus Q3MID3 520 56538 S209 Q A S L E L K S S I I G K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513767 520 56332 S210 K A P L E L K S T I I G K K K
Chicken Gallus gallus Q5F413 428 46296 K162 P I V F E K V K M P Q K K E E
Frog Xenopus laevis NP_001087396 527 57524 A210 V L S T S P K A P V E V K P S
Zebra Danio Brachydanio rerio NP_001032507 536 58567 T210 P S I E G L S T S P K A T I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09531 529 57893 K212 V I L K K P I K K A T L G A K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIQ0 402 43532 S136 T V L P S L S S V A T S Q P V
Baker's Yeast Sacchar. cerevisiae P38682 493 55075 T220 K T R S S I L T A S R K K P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 93.4 N.A. 92.5 93 N.A. 86.3 20.1 72.8 70.3 N.A. N.A. N.A. 34.5 N.A.
Protein Similarity: 100 99.8 98.8 96.7 N.A. 96.9 97.1 N.A. 91.7 37 82.9 83.9 N.A. N.A. N.A. 54 N.A.
P-Site Identity: 100 100 100 26.6 N.A. 93.3 93.3 N.A. 86.6 13.3 20 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 100 100 N.A. 93.3 26.6 33.3 26.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.7 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. 45.8 43.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 47 0 0 0 0 0 8 8 16 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 16 54 0 0 0 0 0 8 0 0 8 8 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 8 47 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 8 0 0 8 8 0 0 54 47 0 0 8 0 % I
% Lys: 39 0 0 8 8 8 54 16 8 0 8 24 77 54 54 % K
% Leu: 0 8 24 47 0 62 8 0 8 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 16 0 8 8 8 16 0 0 8 16 0 0 0 24 8 % P
% Gln: 16 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % Q
% Arg: 0 0 8 0 0 8 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 16 47 8 24 0 16 62 47 8 0 8 0 0 8 % S
% Thr: 8 8 0 8 0 0 8 16 8 0 16 0 8 0 0 % T
% Val: 16 8 8 0 0 0 8 0 8 8 0 8 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _