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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTUD6B All Species: 26.06
Human Site: S189 Identified Species: 57.33
UniProt: Q8N6M0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N6M0 NP_057107.3 293 33813 S189 Q T A E Y M Q S H V E D F L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086186 293 33735 S189 Q T A E Y M Q S H V E D F L P
Dog Lupus familis XP_544171 391 43485 G287 Q T A E Y I Q G H V E D F L P
Cat Felis silvestris
Mouse Mus musculus Q8K2H2 294 33740 T190 Q T A E Y M Q T H S D D F L P
Rat Rattus norvegicus NP_001100109 324 37090 S220 Q T A E Y M Q S H S D D F L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIP6 302 34523 S198 Q T A K Y I H S H F D D F L P
Frog Xenopus laevis Q6GM06 294 33413 Y189 L R S Q T A D Y M Q K R A E D
Zebra Danio Brachydanio rerio Q7ZV00 293 33488 S189 Q T A Q Y M R S H A D D F M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623906 297 34672 R194 S K T A I Y L R E N M N E F L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795260 291 33248 S187 K V S D H M K S N I D E F L C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38747 307 36094 Q147 A A L E A S K Q P D L K K M E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.2 67.2 N.A. 88.4 79.3 N.A. N.A. 73.1 69.7 63.1 N.A. N.A. 46.4 N.A. 46.4
Protein Similarity: 100 N.A. 98.9 72.1 N.A. 95.5 86.1 N.A. N.A. 83.7 82.9 77.8 N.A. N.A. 69 N.A. 69.9
P-Site Identity: 100 N.A. 100 86.6 N.A. 80 86.6 N.A. N.A. 66.6 0 66.6 N.A. N.A. 0 N.A. 26.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 20 93.3 N.A. N.A. 6.6 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 64 10 10 10 0 0 0 10 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 10 0 0 10 0 0 10 46 64 0 0 10 % D
% Glu: 0 0 0 55 0 0 0 0 10 0 28 10 10 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 73 10 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 10 0 64 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 19 0 0 0 10 0 0 0 0 0 % I
% Lys: 10 10 0 10 0 0 19 0 0 0 10 10 10 0 0 % K
% Leu: 10 0 10 0 0 0 10 0 0 0 10 0 0 64 10 % L
% Met: 0 0 0 0 0 55 0 0 10 0 10 0 0 19 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 64 % P
% Gln: 64 0 0 19 0 0 46 10 0 10 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 10 10 0 0 0 10 0 0 0 % R
% Ser: 10 0 19 0 0 10 0 55 0 19 0 0 0 0 0 % S
% Thr: 0 64 10 0 10 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 28 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 64 10 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _