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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AOPEP
All Species:
22.42
Human Site:
T258
Identified Species:
54.81
UniProt:
Q8N6M6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N6M6
NP_116212.3
819
93572
T258
K
P
E
G
R
S
V
T
W
T
S
D
Q
S
G
Chimpanzee
Pan troglodytes
XP_001150193
819
93483
T258
K
P
E
G
R
S
V
T
W
T
S
D
Q
S
G
Rhesus Macaque
Macaca mulatta
XP_001105417
819
92641
T258
K
P
E
G
R
S
V
T
W
T
S
D
Q
S
G
Dog
Lupus familis
XP_848283
819
93374
T258
K
P
Q
G
R
S
V
T
W
T
S
D
Q
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXQ6
817
92937
A258
K
P
E
G
Q
S
V
A
W
T
T
D
Q
N
G
Rat
Rattus norvegicus
P69527
816
92818
T258
K
P
E
G
Q
S
V
T
W
T
S
D
Q
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231898
826
93758
T260
K
P
E
G
R
S
V
T
W
T
T
D
Q
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116730
787
89175
G242
R
C
C
V
Y
T
M
G
S
P
I
N
N
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193484
790
88543
Q271
L
H
F
T
D
M
L
Q
P
S
S
I
V
T
L
Poplar Tree
Populus trichocarpa
XP_002316336
620
70279
R133
Q
C
H
P
V
H
A
R
S
V
F
P
C
Q
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
92.8
84.3
N.A.
76.4
77
N.A.
N.A.
71.6
N.A.
54.4
N.A.
N.A.
N.A.
N.A.
37.8
Protein Similarity:
100
99.1
95.8
90.5
N.A.
84.9
84.9
N.A.
N.A.
84
N.A.
67.2
N.A.
N.A.
N.A.
N.A.
56.4
P-Site Identity:
100
100
100
93.3
N.A.
73.3
86.6
N.A.
N.A.
93.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
21.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
10
% A
% Cys:
0
20
10
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
70
0
10
10
% D
% Glu:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
70
0
0
0
10
0
0
0
0
0
0
70
% G
% His:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
10
0
% N
% Pro:
0
70
0
10
0
0
0
0
10
10
0
10
0
0
0
% P
% Gln:
10
0
10
0
20
0
0
10
0
0
0
0
70
10
0
% Q
% Arg:
10
0
0
0
50
0
0
10
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
70
0
0
20
10
60
0
0
50
0
% S
% Thr:
0
0
0
10
0
10
0
60
0
70
20
0
0
10
0
% T
% Val:
0
0
0
10
10
0
70
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _