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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AOPEP All Species: 26.97
Human Site: T271 Identified Species: 65.93
UniProt: Q8N6M6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N6M6 NP_116212.3 819 93572 T271 S G R P C V Y T V G S P I N N
Chimpanzee Pan troglodytes XP_001150193 819 93483 T271 S G R P C V Y T V G S P I N N
Rhesus Macaque Macaca mulatta XP_001105417 819 92641 T271 S G R P C V Y T V G S P V N N
Dog Lupus familis XP_848283 819 93374 T271 S G R P C V Y T M G S P V N N
Cat Felis silvestris
Mouse Mus musculus Q8BXQ6 817 92937 T271 N G R P C V Y T M G S P I N N
Rat Rattus norvegicus P69527 816 92818 T271 D G R P C V Y T M G S P I N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231898 826 93758 T273 S G R P C V Y T M G S P I N N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116730 787 89175 E255 R A L F P C Q E P P V A M S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193484 790 88543 R284 T L A I G G W R C Y N V P V S
Poplar Tree Populus trichocarpa XP_002316336 620 70279 V146 Q D T P A A R V C Y S A K L N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 92.8 84.3 N.A. 76.4 77 N.A. N.A. 71.6 N.A. 54.4 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 99.1 95.8 90.5 N.A. 84.9 84.9 N.A. N.A. 84 N.A. 67.2 N.A. N.A. N.A. N.A. 56.4
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. 93.3 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 100 N.A. 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 21.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 38.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 10 10 0 0 0 0 0 20 0 0 0 % A
% Cys: 0 0 0 0 70 10 0 0 20 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 70 0 0 10 10 0 0 0 70 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 50 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 10 10 0 0 0 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 40 0 0 0 10 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 10 0 0 70 80 % N
% Pro: 0 0 0 80 10 0 0 0 10 10 0 70 10 0 0 % P
% Gln: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 70 0 0 0 10 10 0 0 0 0 0 0 0 % R
% Ser: 50 0 0 0 0 0 0 0 0 0 80 0 0 10 10 % S
% Thr: 10 0 10 0 0 0 0 70 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 70 0 10 30 0 10 10 20 10 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 70 0 0 20 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _