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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AOPEP All Species: 17.58
Human Site: T89 Identified Species: 42.96
UniProt: Q8N6M6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N6M6 NP_116212.3 819 93572 T89 I P V T N A R T F S S E M E Y
Chimpanzee Pan troglodytes XP_001150193 819 93483 T89 I P V T N A R T L S S E M E Y
Rhesus Macaque Macaca mulatta XP_001105417 819 92641 T89 V P V T N A M T F S S E M E Y
Dog Lupus familis XP_848283 819 93374 T89 S P V T D T R T S S S K T G Y
Cat Felis silvestris
Mouse Mus musculus Q8BXQ6 817 92937 T89 V P E M D S S T F S P K M G H
Rat Rattus norvegicus P69527 816 92818 T89 V P K M D S N T F S P K M G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231898 826 93758 V89 F S V S N A S V F S S E V E Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116730 787 89175 H77 Q S Q V S T K H D I N S P I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193484 790 88543 V98 N V S V A K D V R T A R V H V
Poplar Tree Populus trichocarpa XP_002316336 620 70279
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 92.8 84.3 N.A. 76.4 77 N.A. N.A. 71.6 N.A. 54.4 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 99.1 95.8 90.5 N.A. 84.9 84.9 N.A. N.A. 84 N.A. 67.2 N.A. N.A. N.A. N.A. 56.4
P-Site Identity: 100 93.3 86.6 53.3 N.A. 33.3 33.3 N.A. N.A. 60 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 93.3 93.3 66.6 N.A. 66.6 66.6 N.A. N.A. 73.3 N.A. 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 21.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 38.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 0 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 40 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 30 0 10 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 40 0 40 0 % E
% Phe: 10 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 20 % H
% Ile: 20 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % I
% Lys: 0 0 10 0 0 10 10 0 0 0 0 30 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 20 0 0 10 0 0 0 0 0 50 0 0 % M
% Asn: 10 0 0 0 40 0 10 0 0 0 10 0 0 0 0 % N
% Pro: 0 60 0 0 0 0 0 0 0 0 20 0 10 0 0 % P
% Gln: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 30 0 10 0 0 10 0 0 0 % R
% Ser: 10 20 10 10 10 20 20 0 10 70 50 10 0 0 0 % S
% Thr: 0 0 0 40 0 20 0 60 0 10 0 0 10 0 10 % T
% Val: 30 10 50 20 0 0 0 20 0 0 0 0 20 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _