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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL13
All Species:
16.97
Human Site:
S586
Identified Species:
37.33
UniProt:
Q8N6R0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N6R0
NP_001007240.1
699
78768
S586
K
D
P
T
L
G
M
S
C
P
P
P
A
F
V
Chimpanzee
Pan troglodytes
XP_001146517
699
78594
S586
K
D
P
T
L
G
M
S
C
P
P
P
A
F
V
Rhesus Macaque
Macaca mulatta
XP_001100091
699
78534
S586
K
D
P
T
L
G
M
S
C
P
P
P
A
F
V
Dog
Lupus familis
XP_850646
699
78689
C587
D
P
T
L
G
M
S
C
P
P
P
A
F
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR5
698
78738
P587
P
T
L
G
M
S
C
P
P
P
A
F
V
D
Q
Rat
Rattus norvegicus
NP_001127973
705
79579
C593
D
P
T
L
G
M
S
C
P
P
P
A
F
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515064
722
80420
P611
P
T
L
G
M
S
C
P
P
P
A
F
V
D
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NTR1
693
78306
P582
P
S
V
G
M
S
C
P
P
P
A
F
V
E
K
Zebra Danio
Brachydanio rerio
A5WVX1
690
76006
S575
K
D
T
T
L
G
M
S
C
P
P
P
A
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIK9
673
75984
P561
S
L
G
M
S
C
P
P
Q
S
F
L
A
T
K
Honey Bee
Apis mellifera
XP_396079
652
73963
S553
K
D
T
T
V
G
M
S
C
P
P
K
Q
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98
93.7
N.A.
89.9
88.9
N.A.
67.7
N.A.
61.6
53.7
N.A.
42.9
40.9
N.A.
N.A.
Protein Similarity:
100
99.8
99.2
97
N.A.
94.2
94.1
N.A.
78.6
N.A.
76.6
69.8
N.A.
60.2
59.7
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
6.6
13.3
N.A.
6.6
N.A.
6.6
93.3
N.A.
6.6
66.6
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
13.3
N.A.
13.3
93.3
N.A.
6.6
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
28
19
46
0
0
% A
% Cys:
0
0
0
0
0
10
28
19
46
0
0
0
0
0
0
% C
% Asp:
19
46
0
0
0
0
0
0
0
0
0
0
0
19
19
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
28
19
46
0
% F
% Gly:
0
0
10
28
19
46
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
46
0
0
0
0
0
0
0
0
0
0
10
0
0
28
% K
% Leu:
0
10
19
19
37
0
0
0
0
0
0
10
0
0
10
% L
% Met:
0
0
0
10
28
19
46
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
28
19
28
0
0
0
10
37
46
91
64
37
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
10
28
19
46
0
10
0
0
0
0
0
% S
% Thr:
0
19
37
46
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
10
0
10
0
0
0
0
0
0
0
28
19
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _