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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL13 All Species: 36.06
Human Site: Y35 Identified Species: 79.33
UniProt: Q8N6R0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N6R0 NP_001007240.1 699 78768 Y35 A F E W Y G T Y L E L C G V L
Chimpanzee Pan troglodytes XP_001146517 699 78594 Y35 A F E W Y G T Y L E L C G V L
Rhesus Macaque Macaca mulatta XP_001100091 699 78534 Y35 A F E W Y G T Y L E L C G V L
Dog Lupus familis XP_850646 699 78689 Y35 A F E W Y G S Y L E L C G V L
Cat Felis silvestris
Mouse Mus musculus Q91YR5 698 78738 Y35 A F E W Y G T Y L E L C E V L
Rat Rattus norvegicus NP_001127973 705 79579 Y35 T F E W Y G T Y L E L C E V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515064 722 80420 L66 A V L S A R E L G V S R A L T
Chicken Gallus gallus
Frog Xenopus laevis Q6NTR1 693 78306 Y35 A F E W Y G G Y L E L C G L L
Zebra Danio Brachydanio rerio A5WVX1 690 76006 Y35 A F E W Y G D Y N S L C G V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIK9 673 75984 Y35 A F E W Y G E Y L E L C D Q I
Honey Bee Apis mellifera XP_396079 652 73963 Y35 N F E W Y G E Y P E L R S I F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98 93.7 N.A. 89.9 88.9 N.A. 67.7 N.A. 61.6 53.7 N.A. 42.9 40.9 N.A. N.A.
Protein Similarity: 100 99.8 99.2 97 N.A. 94.2 94.1 N.A. 78.6 N.A. 76.6 69.8 N.A. 60.2 59.7 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 6.6 N.A. 86.6 80 N.A. 73.3 53.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. 13.3 N.A. 93.3 80 N.A. 80 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 82 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 82 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 91 0 0 0 28 0 0 82 0 0 19 0 0 % E
% Phe: 0 91 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 91 10 0 10 0 0 0 55 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 10 73 0 91 0 0 19 73 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 19 0 0 0 % R
% Ser: 0 0 0 10 0 0 10 0 0 10 10 0 10 0 0 % S
% Thr: 10 0 0 0 0 0 46 0 0 0 0 0 0 0 10 % T
% Val: 0 10 0 0 0 0 0 0 0 10 0 0 0 64 0 % V
% Trp: 0 0 0 91 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 91 0 0 91 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _