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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC1
All Species:
21.82
Human Site:
S249
Identified Species:
53.33
UniProt:
Q8N7A1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N7A1
NP_751943.1
406
46720
S249
G
E
S
P
K
H
R
S
W
H
T
L
T
P
I
Chimpanzee
Pan troglodytes
XP_509932
441
50654
S284
G
E
S
P
K
H
R
S
W
H
T
L
T
P
I
Rhesus Macaque
Macaca mulatta
XP_001098337
406
46655
S249
G
E
S
P
K
H
R
S
W
H
T
L
T
P
I
Dog
Lupus familis
XP_547799
406
46625
S249
G
E
N
P
K
H
R
S
W
H
T
L
T
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80YG3
406
46812
S249
G
E
S
P
K
H
R
S
W
H
T
L
T
A
I
Rat
Rattus norvegicus
Q3KRE6
406
45907
L248
R
M
N
D
L
H
Y
L
N
L
D
T
W
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515017
375
43054
R222
S
G
E
K
P
K
H
R
S
W
H
T
L
T
P
Chicken
Gallus gallus
XP_421458
404
45904
S251
G
E
K
P
K
D
R
S
W
H
T
L
T
P
I
Frog
Xenopus laevis
Q5U580
411
46740
G246
Q
R
I
Y
V
L
G
G
G
T
S
W
T
A
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002318573
398
44479
K245
H
S
T
V
S
F
G
K
N
L
F
V
F
G
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.7
99
94
N.A.
88.6
43
N.A.
77
82.2
20.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87.9
99.2
96.5
N.A.
94.8
60
N.A.
84.4
90.6
37.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
0
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
0
86.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
60
10
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% F
% Gly:
60
10
0
0
0
0
20
10
10
0
0
0
0
10
10
% G
% His:
10
0
0
0
0
60
10
0
0
60
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
60
% I
% Lys:
0
0
10
10
60
10
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
10
0
10
0
20
0
60
10
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
20
0
0
0
0
0
20
0
0
0
0
0
0
% N
% Pro:
0
0
0
60
10
0
0
0
0
0
0
0
0
50
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
0
60
10
0
0
0
0
0
0
0
% R
% Ser:
10
10
40
0
10
0
0
60
10
0
10
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
10
60
20
70
10
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
60
10
0
10
10
0
10
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _