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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF645
All Species:
0
Human Site:
S357
Identified Species:
0
UniProt:
Q8N7E2
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N7E2
NP_689790.1
425
48785
S357
P
S
A
S
E
F
A
S
H
H
Y
N
L
N
I
Chimpanzee
Pan troglodytes
XP_001148913
338
38413
E271
A
P
A
H
H
H
P
E
Y
Q
G
Q
P
V
V
Rhesus Macaque
Macaca mulatta
XP_001094529
491
54487
P421
P
P
V
T
A
P
P
P
H
H
Y
N
P
N
S
Dog
Lupus familis
XP_540381
515
57165
P445
P
P
V
T
A
P
P
P
H
H
Y
N
P
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIY2
491
54426
P421
P
P
V
T
A
P
P
P
H
H
Y
N
P
N
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHZ4
493
54832
V416
P
Q
H
G
G
P
P
V
N
V
S
A
P
P
P
Frog
Xenopus laevis
Q4V7X9
496
55521
N424
Q
H
G
G
P
P
V
N
A
P
P
P
H
H
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002308203
336
36852
Q269
S
N
P
L
L
T
P
Q
F
G
L
P
P
F
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.5
48.4
46.2
N.A.
47.8
N.A.
N.A.
N.A.
45.2
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
54.8
59.8
56.5
N.A.
59.4
N.A.
N.A.
N.A.
58.2
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
40
40
N.A.
40
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
46.6
46.6
N.A.
46.6
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
25
0
38
0
13
0
13
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
13
0
0
0
0
13
0
% F
% Gly:
0
0
13
25
13
0
0
0
0
13
13
0
0
0
0
% G
% His:
0
13
13
13
13
13
0
0
50
50
0
0
13
13
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
13
13
0
0
0
0
0
13
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
13
13
0
0
50
0
50
0
% N
% Pro:
63
50
13
0
13
63
75
38
0
13
13
25
75
13
13
% P
% Gln:
13
13
0
0
0
0
0
13
0
13
0
13
0
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
13
0
13
0
0
0
13
0
0
13
0
0
0
38
% S
% Thr:
0
0
0
38
0
13
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
38
0
0
0
13
13
0
13
0
0
0
13
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
50
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _