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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU5F2 All Species: 8.18
Human Site: S310 Identified Species: 18
UniProt: Q8N7G0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N7G0 NP_694948.1 328 36051 S310 P H Y T R L Y S A G V A H S S
Chimpanzee Pan troglodytes Q7YR49 360 38582 S335 P H F T A L Y S S V P F P E G
Rhesus Macaque Macaca mulatta Q5TM49 360 38511 P340 L Y S S V P F P E G E A F P P
Dog Lupus familis XP_538830 360 38329 S335 P H F T T L Y S S V P L P E G
Cat Felis silvestris
Mouse Mus musculus Q9DAC9 329 36392 P309 L Y S S T P F P V R G A L L S
Rat Rattus norvegicus P56225 335 36982 P315 L Y S S T P F P V R G A L L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001103648 295 33223 S266 Q G Y S L A P S P P V Y M P P
Frog Xenopus laevis B7ZQA9 445 49017 P409 V M P S Q V F P T V P L G A N
Zebra Danio Brachydanio rerio Q90270 472 51486 R454 L Y M P S L H R P D V F K N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 T399 M H G S P M G T H S H S H S P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P20268 380 42556 A360 N N G Y P M T A D L F P Y Q A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.2 48 47.7 N.A. 65.9 65.3 N.A. N.A. 35 28.9 29 N.A. 28.5 N.A. 30 N.A.
Protein Similarity: 100 58.8 58.6 59.1 N.A. 76.9 76.7 N.A. N.A. 48.4 40.2 41.3 N.A. 41.9 N.A. 43.4 N.A.
P-Site Identity: 100 40 13.3 40 N.A. 13.3 13.3 N.A. N.A. 20 0 13.3 N.A. 20 N.A. 0 N.A.
P-Site Similarity: 100 53.3 33.3 53.3 N.A. 33.3 33.3 N.A. N.A. 26.6 40 33.3 N.A. 46.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 0 10 10 0 0 37 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 10 0 0 19 0 % E
% Phe: 0 0 19 0 0 0 37 0 0 0 10 19 10 0 0 % F
% Gly: 0 10 19 0 0 0 10 0 0 19 19 0 10 0 28 % G
% His: 0 37 0 0 0 0 10 0 10 0 10 0 19 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 37 0 0 0 10 37 0 0 0 10 0 19 19 19 0 % L
% Met: 10 10 10 0 0 19 0 0 0 0 0 0 10 0 0 % M
% Asn: 10 10 0 0 0 0 0 0 0 0 0 0 0 10 10 % N
% Pro: 28 0 10 10 19 28 10 37 19 10 28 10 19 19 28 % P
% Gln: 10 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 10 0 0 10 0 19 0 0 0 0 0 % R
% Ser: 0 0 28 55 10 0 0 37 19 10 0 10 0 19 28 % S
% Thr: 0 0 0 28 28 0 10 10 10 0 0 0 0 0 0 % T
% Val: 10 0 0 0 10 10 0 0 19 28 28 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 37 19 10 0 0 28 0 0 0 0 10 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _