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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM123A All Species: 17.27
Human Site: S395 Identified Species: 54.29
UniProt: Q8N7J2 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N7J2 NP_689917.2 671 69549 S395 Q E E E A G P S C D K H V P G
Chimpanzee Pan troglodytes XP_509590 678 70267 S402 Q E E E A G P S C D K H V P G
Rhesus Macaque Macaca mulatta XP_001091262 672 69356 S396 P E E E A G P S C D K H A P G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8CCJ4 672 69914 S396 P E E E A G P S C D K H V P G
Rat Rattus norvegicus XP_573799 671 69883 S395 P E E E A G P S C D K H A P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519316 362 37728 S110 E G W A T L S S E H A G P E P
Chicken Gallus gallus XP_417133 497 52281 A245 K K H P T M V A Y Q G G G E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001093622 654 69132 C378 L A S I H A S C Y M P A H Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 94.7 N.A. N.A. 79.6 80 N.A. 28 49.9 N.A. 20.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.5 95 N.A. N.A. 84.5 84.5 N.A. 34.8 57.3 N.A. 35.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 N.A. N.A. 93.3 86.6 N.A. 6.6 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 N.A. N.A. 93.3 86.6 N.A. 13.3 20 N.A. 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 13 63 13 0 13 0 0 13 13 25 0 0 % A
% Cys: 0 0 0 0 0 0 0 13 63 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0 % D
% Glu: 13 63 63 63 0 0 0 0 13 0 0 0 0 25 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 0 0 0 63 0 0 0 0 13 25 13 0 63 % G
% His: 0 0 13 0 13 0 0 0 0 13 0 63 13 0 0 % H
% Ile: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 13 0 0 0 0 0 0 0 0 63 0 0 0 0 % K
% Leu: 13 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 13 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 38 0 0 13 0 0 63 0 0 0 13 0 13 63 13 % P
% Gln: 25 0 0 0 0 0 0 0 0 13 0 0 0 13 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % R
% Ser: 0 0 13 0 0 0 25 75 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 13 0 0 0 0 0 38 0 0 % V
% Trp: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _