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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHB
All Species:
13.64
Human Site:
S771
Identified Species:
42.86
UniProt:
Q8N7U6
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N7U6
NP_653316.3
831
93557
S771
R
D
F
F
K
T
R
S
K
E
E
I
A
E
I
Chimpanzee
Pan troglodytes
XP_516318
669
76388
D626
N
I
G
V
K
L
S
D
E
E
F
E
N
V
W
Rhesus Macaque
Macaca mulatta
XP_001088383
669
76125
D626
N
I
G
V
K
L
S
D
E
E
F
E
N
V
W
Dog
Lupus familis
XP_542768
881
99192
S821
R
D
F
F
K
T
R
S
K
K
E
I
A
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU5
853
95666
S793
R
D
F
F
K
T
R
S
K
E
E
I
S
D
I
Rat
Rattus norvegicus
NP_001100349
852
95791
S793
R
D
F
F
K
T
R
S
K
E
E
I
S
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425999
612
68605
V569
Q
I
L
Q
N
I
G
V
N
I
S
D
E
R
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783931
592
66072
L549
D
P
E
T
F
H
K
L
W
S
V
A
T
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
76.5
74.6
N.A.
66.5
66.6
N.A.
N.A.
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
79.9
78.6
82.1
N.A.
76.6
77.1
N.A.
N.A.
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.7
P-Site Identity:
100
13.3
13.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
13
25
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
50
0
0
0
0
0
25
0
0
0
13
0
25
0
% D
% Glu:
0
0
13
0
0
0
0
0
25
63
50
25
13
25
0
% E
% Phe:
0
0
50
50
13
0
0
0
0
0
25
0
0
0
13
% F
% Gly:
0
0
25
0
0
0
13
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
38
0
0
0
13
0
0
0
13
0
50
0
0
50
% I
% Lys:
0
0
0
0
75
0
13
0
50
13
0
0
0
0
0
% K
% Leu:
0
0
13
0
0
25
0
13
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
0
0
0
13
0
0
0
13
0
0
0
25
0
0
% N
% Pro:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
0
0
0
0
0
50
0
0
0
0
0
0
13
13
% R
% Ser:
0
0
0
0
0
0
25
50
0
13
13
0
25
13
0
% S
% Thr:
0
0
0
13
0
50
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
25
0
0
0
13
0
0
13
0
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
25
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _