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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFHB All Species: 12.73
Human Site: S787 Identified Species: 40
UniProt: Q8N7U6 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N7U6 NP_653316.3 831 93557 S787 C N I G V K L S D E E F E N V
Chimpanzee Pan troglodytes XP_516318 669 76388 H641 N L A S K K H H R G E V C V E
Rhesus Macaque Macaca mulatta XP_001088383 669 76125 H641 N L A S K K H H R G E V C V E
Dog Lupus familis XP_542768 881 99192 S837 C N I G V K L S D E E F E N V
Cat Felis silvestris
Mouse Mus musculus Q8CDU5 853 95666 S809 T N I G V K L S K E E F E N V
Rat Rattus norvegicus NP_001100349 852 95791 T809 T N I G V K L T E E E F E N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425999 612 68605 C584 E D I W K Q A C M K Q Q K E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783931 592 66072 V564 S E Q G Q V S V E S F R N V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 76.5 74.6 N.A. 66.5 66.6 N.A. N.A. 45.7 N.A. N.A. N.A. N.A. N.A. N.A. 34.7
Protein Similarity: 100 79.9 78.6 82.1 N.A. 76.6 77.1 N.A. N.A. 58.2 N.A. N.A. N.A. N.A. N.A. N.A. 49.7
P-Site Identity: 100 13.3 13.3 100 N.A. 86.6 80 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 13.3 13.3 100 N.A. 86.6 93.3 N.A. N.A. 40 N.A. N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 25 0 0 0 13 0 0 0 0 0 0 0 0 % A
% Cys: 25 0 0 0 0 0 0 13 0 0 0 0 25 0 0 % C
% Asp: 0 13 0 0 0 0 0 0 25 0 0 0 0 0 0 % D
% Glu: 13 13 0 0 0 0 0 0 25 50 75 0 50 13 38 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 13 50 0 0 0 % F
% Gly: 0 0 0 63 0 0 0 0 0 25 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 25 25 0 0 0 0 0 0 0 % H
% Ile: 0 0 63 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 38 75 0 0 13 13 0 0 13 0 0 % K
% Leu: 0 25 0 0 0 0 50 0 0 0 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % M
% Asn: 25 50 0 0 0 0 0 0 0 0 0 0 13 50 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 13 0 13 13 0 0 0 0 13 13 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 25 0 0 13 0 0 0 % R
% Ser: 13 0 0 25 0 0 13 38 0 13 0 0 0 0 0 % S
% Thr: 25 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 50 13 0 13 0 0 0 25 0 38 50 % V
% Trp: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _