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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 5.45
Human Site: T370 Identified Species: 12
UniProt: Q8N819 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N819 NP_001073870.1 430 46170 T370 S L N T V F R T L A S E D I P
Chimpanzee Pan troglodytes XP_512750 397 43055 A336 A P R P S E E A I R R E L A L
Rhesus Macaque Macaca mulatta XP_001111662 479 52622 I341 D L A H V M R I L S A E N I P
Dog Lupus familis XP_541558 501 53663 T362 S L N T V F W T L A S E D I P
Cat Felis silvestris
Mouse Mus musculus Q8BGL1 404 43183 L347 L S H K V A E L Y A S A Q E P
Rat Rattus norvegicus P35815 390 42871 M332 Q K S G E E G M P D L A H V M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421422 382 42461 G324 E E I I K K Q G E G V P D L V
Frog Xenopus laevis NP_001085063 455 50420 I341 D L A H V M R I L A A E N I P
Zebra Danio Brachydanio rerio NP_001007314 382 42180 E325 L M E K S G E E G I P D L S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49596 356 39046 K298 S P D T L F T K C A R P A V F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81716 355 39336 S298 L K S E T K L S T V C E K V V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 36.1 70.2 N.A. 71.4 38.8 N.A. N.A. 40 36.4 42.7 N.A. N.A. N.A. 28.3 N.A.
Protein Similarity: 100 88.1 48.2 74.8 N.A. 78.3 50.9 N.A. N.A. 54.8 49.4 56.2 N.A. N.A. N.A. 42.3 N.A.
P-Site Identity: 100 6.6 46.6 93.3 N.A. 26.6 0 N.A. N.A. 6.6 53.3 0 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 20 66.6 93.3 N.A. 33.3 13.3 N.A. N.A. 20 66.6 13.3 N.A. N.A. N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 0 0 10 0 10 0 46 19 19 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % C
% Asp: 19 0 10 0 0 0 0 0 0 10 0 10 28 0 0 % D
% Glu: 10 10 10 10 10 19 28 10 10 0 0 55 0 10 0 % E
% Phe: 0 0 0 0 0 28 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 10 0 10 10 10 10 10 0 0 0 0 0 % G
% His: 0 0 10 19 0 0 0 0 0 0 0 0 10 0 10 % H
% Ile: 0 0 10 10 0 0 0 19 10 10 0 0 0 37 0 % I
% Lys: 0 19 0 19 10 19 0 10 0 0 0 0 10 0 0 % K
% Leu: 28 37 0 0 10 0 10 10 37 0 10 0 19 10 10 % L
% Met: 0 10 0 0 0 19 0 10 0 0 0 0 0 0 10 % M
% Asn: 0 0 19 0 0 0 0 0 0 0 0 0 19 0 0 % N
% Pro: 0 19 0 10 0 0 0 0 10 0 10 19 0 0 46 % P
% Gln: 10 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 10 0 0 0 28 0 0 10 19 0 0 0 0 % R
% Ser: 28 10 19 0 19 0 0 10 0 10 28 0 0 10 0 % S
% Thr: 0 0 0 28 10 0 10 19 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 46 0 0 0 0 10 10 0 0 28 19 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _