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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TCEANC All Species: 17.88
Human Site: S249 Identified Species: 49.17
UniProt: Q8N8B7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N8B7 NP_689847 351 40245 S249 N L L S G T T S P R E F A E M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537955 348 39922 S246 N L L S G T M S P R E F A K M
Cat Felis silvestris
Mouse Mus musculus Q3US16 359 40617 S258 N F L S G T M S A R E F A E M
Rat Rattus norvegicus Q63799 299 33509 D198 S R I S N L K D A K N P G L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515301 359 40420 T257 N L F S G S L T P E A F A E M
Chicken Gallus gallus XP_416834 359 40903 S257 N L F S G T L S P K A F A E M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919157 394 44491 T292 G L I S G Q L T P D A F A Q M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20232 313 34282 D212 S R V A N L K D P K N P G L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52652 308 34854 D207 S R I F N L R D K K N L A L R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 79.1 N.A. 67.6 30.2 N.A. 57.9 53.2 N.A. 37.3 N.A. 29 N.A. 26.5 N.A.
Protein Similarity: 100 N.A. N.A. 86.8 N.A. 76.8 49.2 N.A. 73.8 67.6 N.A. 57.8 N.A. 49.2 N.A. 48.7 N.A.
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 80 6.6 N.A. 60 73.3 N.A. 46.6 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 80 26.6 N.A. 73.3 80 N.A. 66.6 N.A. 33.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 0 23 0 34 0 78 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 34 0 12 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 12 34 0 0 45 0 % E
% Phe: 0 12 23 12 0 0 0 0 0 0 0 67 0 0 0 % F
% Gly: 12 0 0 0 67 0 0 0 0 0 0 0 23 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 23 0 12 45 0 0 0 12 0 % K
% Leu: 0 56 34 0 0 34 34 0 0 0 0 12 0 34 0 % L
% Met: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 67 % M
% Asn: 56 0 0 0 34 0 0 0 0 0 34 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 67 0 0 23 0 0 0 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 0 0 0 12 0 % Q
% Arg: 0 34 0 0 0 0 12 0 0 34 0 0 0 0 34 % R
% Ser: 34 0 0 78 0 12 0 45 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 45 12 23 0 0 0 0 0 0 0 % T
% Val: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _