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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC46
All Species:
23.64
Human Site:
T589
Identified Species:
52
UniProt:
Q8N8E3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8E3
NP_001032402.1
955
112749
T589
E
E
Q
L
T
R
V
T
E
V
Q
R
L
Q
A
Chimpanzee
Pan troglodytes
XP_001163511
955
112710
T589
E
E
Q
L
T
R
V
T
E
V
Q
R
L
Q
A
Rhesus Macaque
Macaca mulatta
XP_001116761
955
112893
T589
E
E
Q
L
T
R
V
T
E
V
Q
R
L
Q
A
Dog
Lupus familis
XP_537580
250
29557
Cat
Felis silvestris
Mouse
Mus musculus
Q5PR68
954
112657
T588
E
E
Q
L
S
R
V
T
E
V
Q
R
L
Q
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508857
952
111846
T586
E
E
Q
L
T
R
V
T
E
I
Q
K
L
Q
A
Chicken
Gallus gallus
P14105
1959
226485
T1329
R
L
K
L
S
F
S
T
K
L
K
Q
T
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
N1311
E
D
A
E
S
Q
V
N
Q
L
T
R
L
K
S
Sea Urchin
Strong. purpuratus
XP_781919
950
112128
K571
D
E
Q
I
K
R
L
K
E
L
Q
R
L
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LW85
726
81954
L450
L
E
G
T
K
K
T
L
Q
A
S
R
D
R
V
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
S1334
E
K
S
E
S
E
L
S
R
L
K
K
T
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
23.8
N.A.
86.6
N.A.
N.A.
75.2
20.7
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
41
Protein Similarity:
100
99.9
99.5
25.4
N.A.
93.5
N.A.
N.A.
87.7
34.5
N.A.
N.A.
N.A.
N.A.
N.A.
33.6
63.8
P-Site Identity:
100
100
100
0
N.A.
93.3
N.A.
N.A.
86.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
60
P-Site Similarity:
100
100
100
0
N.A.
100
N.A.
N.A.
100
60
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.7
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% D
% Glu:
64
64
0
19
0
10
0
0
55
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
10
0
19
10
0
10
10
0
19
19
0
10
0
% K
% Leu:
10
10
0
55
0
0
19
10
0
37
0
0
64
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
55
0
0
10
0
0
19
0
55
10
0
55
0
% Q
% Arg:
10
0
0
0
0
55
0
0
10
0
0
64
0
10
0
% R
% Ser:
0
0
10
0
37
0
10
10
0
0
10
0
0
10
19
% S
% Thr:
0
0
0
10
37
0
10
55
0
0
10
0
19
0
0
% T
% Val:
0
0
0
0
0
0
55
0
0
37
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _