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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC46
All Species:
21.82
Human Site:
Y473
Identified Species:
48
UniProt:
Q8N8E3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8E3
NP_001032402.1
955
112749
Y473
K
D
H
L
V
N
D
Y
E
Q
N
M
K
L
L
Chimpanzee
Pan troglodytes
XP_001163511
955
112710
Y473
K
D
H
L
V
N
D
Y
E
Q
N
M
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001116761
955
112893
Y473
K
D
H
L
V
N
D
Y
E
Q
N
M
K
L
L
Dog
Lupus familis
XP_537580
250
29557
Cat
Felis silvestris
Mouse
Mus musculus
Q5PR68
954
112657
Y472
K
E
H
L
V
N
D
Y
E
Q
N
V
K
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508857
952
111846
Y470
R
D
H
I
I
Q
D
Y
E
K
N
I
K
L
L
Chicken
Gallus gallus
P14105
1959
226485
L1172
R
E
Q
E
V
T
V
L
K
K
T
L
E
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
L1186
R
E
A
E
L
A
K
L
R
R
D
L
E
E
A
Sea Urchin
Strong. purpuratus
XP_781919
950
112128
Y455
Y
D
L
K
K
I
D
Y
E
R
E
L
K
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LW85
726
81954
R347
A
I
E
E
L
N
T
R
I
T
T
L
V
A
E
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
S1214
V
K
A
M
K
S
T
S
E
E
Q
S
N
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
23.8
N.A.
86.6
N.A.
N.A.
75.2
20.7
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
41
Protein Similarity:
100
99.9
99.5
25.4
N.A.
93.5
N.A.
N.A.
87.7
34.5
N.A.
N.A.
N.A.
N.A.
N.A.
33.6
63.8
P-Site Identity:
100
100
100
0
N.A.
86.6
N.A.
N.A.
60
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
40
P-Site Similarity:
100
100
100
0
N.A.
100
N.A.
N.A.
93.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.7
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
0
10
0
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
0
0
0
55
0
0
0
10
0
0
10
0
% D
% Glu:
0
28
10
28
0
0
0
0
64
10
10
0
19
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
10
10
0
0
10
0
0
10
0
0
0
% I
% Lys:
37
10
0
10
19
0
10
0
10
19
0
0
55
0
10
% K
% Leu:
0
0
10
37
19
0
0
19
0
0
0
37
0
55
55
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
28
0
0
0
% M
% Asn:
0
0
0
0
0
46
0
0
0
0
46
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
10
0
0
0
37
10
0
0
0
0
% Q
% Arg:
28
0
0
0
0
0
0
10
10
19
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
10
19
0
0
10
19
0
0
0
0
% T
% Val:
10
0
0
0
46
0
10
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _