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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VGLL2
All Species:
11.52
Human Site:
S270
Identified Species:
31.67
UniProt:
Q8N8G2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8G2
NP_703154.1
317
33426
S270
G
S
P
P
C
E
L
S
G
K
G
E
P
A
G
Chimpanzee
Pan troglodytes
XP_001162679
317
33397
S270
G
S
P
P
C
E
L
S
G
K
G
E
P
A
G
Rhesus Macaque
Macaca mulatta
XP_001110896
317
33444
S270
G
S
P
P
C
E
L
S
G
K
G
E
P
A
G
Dog
Lupus familis
XP_541214
338
35855
S271
G
S
P
P
C
E
L
S
K
G
E
P
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW8
322
34045
A268
S
P
P
C
E
L
A
A
K
G
E
P
A
G
S
Rat
Rattus norvegicus
NP_001101100
323
34197
A268
G
S
P
P
C
E
L
A
A
K
G
E
P
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515239
442
48993
P385
H
G
T
V
D
I
V
P
S
F
G
F
D
T
G
Chicken
Gallus gallus
NP_001139462
303
32480
E260
P
C
E
L
G
K
G
E
A
G
P
A
A
A
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001020657
296
32284
D254
A
P
G
S
S
P
C
D
I
S
K
S
E
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.1
87.8
N.A.
85.7
84.5
N.A.
27.6
72.2
N.A.
59.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
98.4
88.4
N.A.
89.4
89.4
N.A.
37.3
78.5
N.A.
69.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
53.3
N.A.
6.6
86.6
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
13.3
93.3
N.A.
20
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
12
23
23
0
0
12
34
67
12
% A
% Cys:
0
12
0
12
56
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
12
0
0
0
0
12
0
0
% D
% Glu:
0
0
12
0
12
56
0
12
0
0
23
45
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% F
% Gly:
56
12
12
0
12
0
12
0
34
34
56
0
0
23
67
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
23
45
12
0
0
0
0
% K
% Leu:
0
0
0
12
0
12
56
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
23
67
56
0
12
0
12
0
0
12
23
45
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
56
0
12
12
0
0
45
12
12
0
12
0
0
12
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _