KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
5.45
Human Site:
S275
Identified Species:
20
UniProt:
Q8N8Q3
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8Q3
NP_001158109.1
282
30792
S275
V
A
C
P
K
G
D
S
G
E
S
S
A
L
C
Chimpanzee
Pan troglodytes
XP_001161219
310
33758
S276
V
A
C
P
K
R
D
S
G
E
S
S
G
E
G
Rhesus Macaque
Macaca mulatta
XP_001110357
390
42899
Dog
Lupus familis
XP_850549
442
47939
A275
K
I
R
W
E
S
L
A
R
M
V
T
A
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420082
285
31139
H275
A
E
L
E
G
K
S
H
S
G
R
N
G
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794487
329
36819
D277
K
H
R
K
K
D
P
D
G
A
L
G
K
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567868
277
30863
S263
L
Q
K
H
Q
T
E
S
F
K
E
L
A
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
60.5
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.2
Protein Similarity:
100
85.1
62.3
58.1
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
61.7
P-Site Identity:
100
73.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
73.3
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
29
0
0
0
0
0
15
0
15
0
0
43
0
0
% A
% Cys:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
0
0
0
0
15
29
15
0
0
0
0
0
0
15
% D
% Glu:
0
15
0
15
15
0
15
0
0
29
15
0
0
29
15
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
15
0
0
43
15
0
15
29
15
29
% G
% His:
0
15
0
15
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
29
0
15
15
43
15
0
0
0
15
0
0
15
0
0
% K
% Leu:
15
0
15
0
0
0
15
0
0
0
15
15
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% N
% Pro:
0
0
0
29
0
0
15
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
15
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
29
0
0
15
0
0
15
0
15
0
0
0
15
% R
% Ser:
0
0
0
0
0
15
15
43
15
0
29
29
0
0
0
% S
% Thr:
0
0
0
0
0
15
0
0
0
0
0
15
0
15
0
% T
% Val:
29
0
0
0
0
0
0
0
0
0
15
0
0
15
0
% V
% Trp:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _