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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX18
All Species:
21.82
Human Site:
S198
Identified Species:
40
UniProt:
Q8N8Q8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8Q8
NP_776188.1
333
37063
S198
L
S
T
G
A
A
H
S
E
G
F
S
V
Q
E
Chimpanzee
Pan troglodytes
XP_517237
334
37115
S198
L
S
T
G
A
A
H
S
E
A
G
F
S
V
Q
Rhesus Macaque
Macaca mulatta
XP_001104459
333
36848
S198
L
S
T
G
A
A
H
S
E
G
F
S
V
Q
E
Dog
Lupus familis
XP_539312
333
36491
S197
F
S
T
G
A
A
H
S
E
A
G
F
S
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC74
331
36343
S195
L
S
T
G
A
T
H
S
D
G
I
S
V
Q
E
Rat
Rattus norvegicus
NP_001099470
331
36300
S195
L
S
T
G
A
T
H
S
D
G
I
S
V
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511643
248
27826
D119
F
P
D
L
T
V
L
D
S
T
L
I
L
P
V
Chicken
Gallus gallus
XP_420604
364
40246
S185
C
S
V
G
A
L
D
S
E
V
Q
E
Q
F
S
Frog
Xenopus laevis
NP_001090111
381
42844
D245
I
S
L
N
R
T
A
D
T
T
G
D
A
V
Q
Zebra Danio
Brachydanio rerio
NP_001107941
328
36390
T191
L
S
L
G
L
G
N
T
D
V
S
A
G
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648286
351
39277
P202
L
V
Y
M
L
P
D
P
T
S
I
Q
A
Q
I
Honey Bee
Apis mellifera
XP_001120913
347
40227
V206
I
C
Y
M
L
P
Q
V
N
T
A
T
L
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784727
340
38561
R180
M
T
G
A
L
S
E
R
M
Y
V
V
P
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.9
79.2
N.A.
77.1
75.6
N.A.
49.2
52.7
50.1
52.2
N.A.
33.9
29.1
N.A.
42.3
Protein Similarity:
100
99.6
95.8
82.5
N.A.
84.9
83.4
N.A.
59.1
64.5
66.6
70.5
N.A.
54.1
51.5
N.A.
59.4
P-Site Identity:
100
60
100
53.3
N.A.
80
73.3
N.A.
0
33.3
6.6
20
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
66.6
100
60
N.A.
86.6
86.6
N.A.
6.6
33.3
20
46.6
N.A.
13.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
54
31
8
0
0
16
8
8
16
0
8
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
16
16
24
0
0
8
0
8
16
% D
% Glu:
0
0
0
0
0
0
8
0
39
0
0
8
0
0
24
% E
% Phe:
16
0
0
0
0
0
0
0
0
0
16
16
0
8
0
% F
% Gly:
0
0
8
62
0
8
0
0
0
31
24
0
8
0
0
% G
% His:
0
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
0
0
0
0
0
24
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
54
0
16
8
31
8
8
0
0
0
8
0
16
8
8
% L
% Met:
8
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
16
0
8
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
8
8
8
47
24
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
70
0
0
0
8
0
54
8
8
8
31
16
0
8
% S
% Thr:
0
8
47
0
8
24
0
8
16
24
0
8
0
0
0
% T
% Val:
0
8
8
0
0
8
0
8
0
16
8
8
31
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _