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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX18
All Species:
12.42
Human Site:
S309
Identified Species:
22.78
UniProt:
Q8N8Q8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8Q8
NP_776188.1
333
37063
S309
R
Q
L
C
R
I
P
S
T
K
S
D
S
E
T
Chimpanzee
Pan troglodytes
XP_517237
334
37115
S310
R
Q
L
C
R
I
P
S
T
K
S
D
S
E
T
Rhesus Macaque
Macaca mulatta
XP_001104459
333
36848
S309
R
Q
L
C
R
I
P
S
T
K
S
D
S
E
T
Dog
Lupus familis
XP_539312
333
36491
L309
R
Q
L
C
R
I
P
L
T
K
S
D
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC74
331
36343
P306
R
Q
L
C
R
I
P
P
S
K
S
D
S
E
T
Rat
Rattus norvegicus
NP_001099470
331
36300
P306
R
Q
L
C
R
I
P
P
S
R
S
D
S
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511643
248
27826
K225
L
R
A
A
F
Y
A
K
Y
L
P
G
K
R
S
Chicken
Gallus gallus
XP_420604
364
40246
R293
R
R
L
C
C
I
P
R
T
K
S
D
S
D
T
Frog
Xenopus laevis
NP_001090111
381
42844
R357
R
R
V
C
R
I
P
R
S
K
S
D
S
D
T
Zebra Danio
Brachydanio rerio
NP_001107941
328
36390
E299
R
K
L
C
R
I
P
E
T
R
F
D
S
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648286
351
39277
K317
R
R
S
V
G
I
P
K
T
Q
T
E
L
S
E
Honey Bee
Apis mellifera
XP_001120913
347
40227
K320
R
R
L
G
K
I
P
K
T
D
S
E
L
R
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784727
340
38561
S289
R
R
A
L
G
M
R
S
S
K
S
D
T
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.9
79.2
N.A.
77.1
75.6
N.A.
49.2
52.7
50.1
52.2
N.A.
33.9
29.1
N.A.
42.3
Protein Similarity:
100
99.6
95.8
82.5
N.A.
84.9
83.4
N.A.
59.1
64.5
66.6
70.5
N.A.
54.1
51.5
N.A.
59.4
P-Site Identity:
100
100
100
80
N.A.
86.6
80
N.A.
0
73.3
66.6
66.6
N.A.
26.6
40
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
13.3
86.6
93.3
86.6
N.A.
53.3
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
70
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
77
0
31
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
16
0
39
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
16
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
85
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
24
0
62
0
0
8
0
0
% K
% Leu:
8
0
70
8
0
0
0
8
0
8
0
0
16
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
85
16
0
0
8
0
0
0
0
% P
% Gln:
0
47
0
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
93
47
0
0
62
0
8
16
0
16
0
0
0
16
8
% R
% Ser:
0
0
8
0
0
0
0
31
31
0
77
0
70
8
16
% S
% Thr:
0
0
0
0
0
0
0
0
62
0
8
0
8
0
70
% T
% Val:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _