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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX18
All Species:
14.55
Human Site:
S31
Identified Species:
26.67
UniProt:
Q8N8Q8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8Q8
NP_776188.1
333
37063
S31
P
L
A
P
V
P
T
S
G
A
K
R
P
T
L
Chimpanzee
Pan troglodytes
XP_517237
334
37115
S31
P
L
A
P
V
P
T
S
G
A
K
R
P
T
L
Rhesus Macaque
Macaca mulatta
XP_001104459
333
36848
S31
A
L
A
P
V
P
T
S
G
A
K
R
P
T
L
Dog
Lupus familis
XP_539312
333
36491
A30
G
G
R
C
P
Q
W
A
R
A
V
A
S
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC74
331
36343
S28
P
R
S
P
P
A
W
S
S
A
R
L
P
A
L
Rat
Rattus norvegicus
NP_001099470
331
36300
S28
P
G
S
L
P
A
W
S
S
A
R
L
P
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511643
248
27826
Chicken
Gallus gallus
XP_420604
364
40246
G18
S
G
S
S
W
Q
L
G
G
A
A
V
A
R
L
Frog
Xenopus laevis
NP_001090111
381
42844
S78
F
V
P
G
S
S
Q
S
R
T
I
C
S
T
T
Zebra Danio
Brachydanio rerio
NP_001107941
328
36390
L24
R
H
G
N
P
A
S
L
R
P
S
L
I
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648286
351
39277
H35
I
A
N
H
T
C
N
H
R
L
S
S
T
E
A
Honey Bee
Apis mellifera
XP_001120913
347
40227
N39
S
T
N
S
I
I
I
N
S
N
R
K
Y
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784727
340
38561
M12
V
Y
Q
C
H
V
G
M
Q
I
P
L
G
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.9
79.2
N.A.
77.1
75.6
N.A.
49.2
52.7
50.1
52.2
N.A.
33.9
29.1
N.A.
42.3
Protein Similarity:
100
99.6
95.8
82.5
N.A.
84.9
83.4
N.A.
59.1
64.5
66.6
70.5
N.A.
54.1
51.5
N.A.
59.4
P-Site Identity:
100
100
93.3
6.6
N.A.
40
40
N.A.
0
20
13.3
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
93.3
13.3
N.A.
53.3
53.3
N.A.
0
26.6
20
20
N.A.
0
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
24
0
0
24
0
8
0
54
8
8
8
8
8
% A
% Cys:
0
0
0
16
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
24
8
8
0
0
8
8
31
0
0
0
8
8
0
% G
% His:
0
8
0
8
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
8
8
0
0
8
8
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
24
8
0
0
0
% K
% Leu:
0
24
0
8
0
0
8
8
0
8
0
31
0
0
47
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
8
0
0
8
8
0
8
0
0
0
0
8
% N
% Pro:
31
0
8
31
31
24
0
0
0
8
8
0
39
0
8
% P
% Gln:
0
0
8
0
0
16
8
0
8
0
0
0
0
0
0
% Q
% Arg:
8
8
8
0
0
0
0
0
31
0
24
24
0
8
0
% R
% Ser:
16
0
24
16
8
8
8
47
24
0
16
8
16
16
8
% S
% Thr:
0
8
0
0
8
0
24
0
0
8
0
0
8
39
8
% T
% Val:
8
8
0
0
24
8
0
0
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
8
0
24
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _