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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX18
All Species:
38.18
Human Site:
S314
Identified Species:
70
UniProt:
Q8N8Q8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8Q8
NP_776188.1
333
37063
S314
I
P
S
T
K
S
D
S
E
T
P
Y
K
D
I
Chimpanzee
Pan troglodytes
XP_517237
334
37115
S315
I
P
S
T
K
S
D
S
E
T
P
Y
K
D
I
Rhesus Macaque
Macaca mulatta
XP_001104459
333
36848
S314
I
P
S
T
K
S
D
S
E
T
P
Y
K
D
I
Dog
Lupus familis
XP_539312
333
36491
S314
I
P
L
T
K
S
D
S
D
S
P
Y
K
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC74
331
36343
S311
I
P
P
S
K
S
D
S
E
T
P
Y
R
D
L
Rat
Rattus norvegicus
NP_001099470
331
36300
S311
I
P
P
S
R
S
D
S
E
T
P
Y
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511643
248
27826
K230
Y
A
K
Y
L
P
G
K
R
S
G
R
R
E
P
Chicken
Gallus gallus
XP_420604
364
40246
S298
I
P
R
T
K
S
D
S
D
T
P
Y
R
D
I
Frog
Xenopus laevis
NP_001090111
381
42844
S362
I
P
R
S
K
S
D
S
D
T
P
Y
K
D
I
Zebra Danio
Brachydanio rerio
NP_001107941
328
36390
S304
I
P
E
T
R
F
D
S
Q
T
P
Y
R
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648286
351
39277
L322
I
P
K
T
Q
T
E
L
S
E
P
Y
D
L
L
Honey Bee
Apis mellifera
XP_001120913
347
40227
L325
I
P
K
T
D
S
E
L
R
R
P
Y
T
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784727
340
38561
T294
M
R
S
S
K
S
D
T
D
T
P
F
L
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.9
79.2
N.A.
77.1
75.6
N.A.
49.2
52.7
50.1
52.2
N.A.
33.9
29.1
N.A.
42.3
Protein Similarity:
100
99.6
95.8
82.5
N.A.
84.9
83.4
N.A.
59.1
64.5
66.6
70.5
N.A.
54.1
51.5
N.A.
59.4
P-Site Identity:
100
100
100
73.3
N.A.
73.3
66.6
N.A.
0
80
80
66.6
N.A.
33.3
40
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
93.3
93.3
86.6
N.A.
60
60
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
77
0
31
0
0
0
8
77
0
% D
% Glu:
0
0
8
0
0
0
16
0
39
8
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
85
0
0
0
0
0
0
0
0
0
0
0
0
0
47
% I
% Lys:
0
0
24
0
62
0
0
8
0
0
0
0
39
0
0
% K
% Leu:
0
0
8
0
8
0
0
16
0
0
0
0
8
8
39
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
85
16
0
0
8
0
0
0
0
93
0
0
0
8
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
16
0
16
0
0
0
16
8
0
8
39
0
0
% R
% Ser:
0
0
31
31
0
77
0
70
8
16
0
0
0
0
0
% S
% Thr:
0
0
0
62
0
8
0
8
0
70
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
0
0
85
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _