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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX18 All Species: 36.67
Human Site: Y104 Identified Species: 67.22
UniProt: Q8N8Q8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N8Q8 NP_776188.1 333 37063 Y104 V T L P L A A Y Q H Y I L A K
Chimpanzee Pan troglodytes XP_517237 334 37115 Y104 V T L P L A A Y Q H Y I L A K
Rhesus Macaque Macaca mulatta XP_001104459 333 36848 Y104 V T L P L A A Y Q H Y I L A K
Dog Lupus familis XP_539312 333 36491 Y103 V T L P L A A Y Q H Y I L A K
Cat Felis silvestris
Mouse Mus musculus Q8VC74 331 36343 Y101 V T L P L A A Y Q H Y I L A K
Rat Rattus norvegicus NP_001099470 331 36300 Y101 V T L P L A A Y Q H Y I L A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511643 248 27826 L29 Y L N H E I S L R A K R L G W
Chicken Gallus gallus XP_420604 364 40246 H91 V T L P L A A H Q G R L L A K
Frog Xenopus laevis NP_001090111 381 42844 Y151 V T L P L S V Y Q M Y I L A K
Zebra Danio Brachydanio rerio NP_001107941 328 36390 Y97 I T L P L A I Y Q A H I I A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648286 351 39277 Y108 V T L P L T I Y Q H K I T A R
Honey Bee Apis mellifera XP_001120913 347 40227 L112 I N L P L N I L D V H T K A K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784727 340 38561 Y85 L T L P L A I Y S Q N I R V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 93.9 79.2 N.A. 77.1 75.6 N.A. 49.2 52.7 50.1 52.2 N.A. 33.9 29.1 N.A. 42.3
Protein Similarity: 100 99.6 95.8 82.5 N.A. 84.9 83.4 N.A. 59.1 64.5 66.6 70.5 N.A. 54.1 51.5 N.A. 59.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 73.3 80 66.6 N.A. 66.6 33.3 N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 86.6 86.6 86.6 N.A. 73.3 46.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 70 54 0 0 16 0 0 0 85 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 8 0 54 16 0 0 0 0 % H
% Ile: 16 0 0 0 0 8 31 0 0 0 0 77 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 16 0 8 0 77 % K
% Leu: 8 8 93 0 93 0 0 16 0 0 0 8 70 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 8 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 77 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 8 8 8 0 16 % R
% Ser: 0 0 0 0 0 8 8 0 8 0 0 0 0 0 0 % S
% Thr: 0 85 0 0 0 8 0 0 0 0 0 8 8 0 0 % T
% Val: 70 0 0 0 0 0 8 0 0 8 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 8 0 0 0 0 0 0 77 0 0 54 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _