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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENAH All Species: 27.58
Human Site: S33 Identified Species: 60.67
UniProt: Q8N8S7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N8S7 NP_001008493.1 591 66510 S33 A G G S T G F S R V H I Y H H
Chimpanzee Pan troglodytes XP_001153142 726 79409 S36 K P G Q Q G F S R I N I Y H N
Rhesus Macaque Macaca mulatta XP_001104614 418 44787 A13 Q S I C Q A R A S V M V Y D D
Dog Lupus familis XP_547511 806 87104 S42 A G G S T G F S R V H I Y H H
Cat Felis silvestris
Mouse Mus musculus Q03173 802 85826 S33 A G G S T G F S R V H I Y H H
Rat Rattus norvegicus O08719 393 42076
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989631 784 84614 S33 A G G S T G F S R V H I Y H H
Frog Xenopus laevis Q64GL0 692 73902 S34 K P G Q Q G F S R I N I Y H N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001014537 687 72309 S33 S G S S S G L S K V Q I Y H H
Honey Bee Apis mellifera XP_001122945 772 80833 S33 S G S S S G L S K V Q L Y H H
Nematode Worm Caenorhab. elegans P46504 980 115327 V219 A F T R P G R V R T T T P M S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.5 40.9 64.3 N.A. 61.2 38.5 N.A. N.A. 48.4 31 N.A. N.A. 32.6 25.6 21.7 N.A.
Protein Similarity: 100 44.4 50 67.6 N.A. 64.5 48.9 N.A. N.A. 55.8 44.9 N.A. N.A. 47 42.3 33.7 N.A.
P-Site Identity: 100 53.3 13.3 100 N.A. 100 0 N.A. N.A. 100 53.3 N.A. N.A. 60 53.3 20 N.A.
P-Site Similarity: 100 73.3 26.6 100 N.A. 100 0 N.A. N.A. 100 73.3 N.A. N.A. 80 80 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 55 0 0 0 0 0 0 0 0 % F
% Gly: 0 55 55 0 0 82 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 37 0 0 73 55 % H
% Ile: 0 0 10 0 0 0 0 0 0 19 0 64 0 0 0 % I
% Lys: 19 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 19 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 19 % N
% Pro: 0 19 0 0 10 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 10 0 0 19 28 0 0 0 0 0 19 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 19 0 64 0 0 0 0 0 0 % R
% Ser: 19 10 19 55 19 0 0 73 10 0 0 0 0 0 10 % S
% Thr: 0 0 10 0 37 0 0 0 0 10 10 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 64 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 82 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _